Page 727 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

APPENDIX C ■ Safety Data Sheets 711

■ Any special requirements or PPE, protective clothing, or ■ In ication o any sa ety issues that may arise shoul the
respirators (e.g., type o glove material, such as PVC or pro uct change in physical appearance

nitrile rubber gloves; an breakthrough time o the glove Other

material)

■ In ication o the possibility o hazar ous reactions, inclu -
ing a statement whether the chemical will react or polym-
SECTION 9: PHYSICAL AND CHEMICAL erize, which coul release excess pressure or heat, or create

PROPERTIES other hazar ous con itions. Also, a escription o the con-

itions un er which hazar ous reactions may occur.
Tis section i entif es physical an chemical properties asso- ■ List o all con itions that shoul be avoi e (e.g., static

ciate with the substance or mixture. T e minimum require ischarge, shock, vibrations, or environmental con itions

in ormation consists o
that may lea to hazar ous con itions).

■ Appearance (physical state, color, etc.) ■ List o all classes o incompatible materials (e.g., classes o

■ Upper/lower ammability or explosive limits chemicals or specif c substances) with which the chemical

■ O or coul react to pro uce a hazar ous situation.

■ Vapor pressure ■ List o any known or anticipate hazar ous ecomposition

■ O or threshol pro ucts that coul be pro uce because o use, storage, or

■ Vapor ensity heating. (Hazar ous combustion pro ucts shoul also be

■ pH inclu e in Section 5 [Fire-Fighting Measures] o the SDS.)

■ Relative ensity

■ Melting point/ reezing point

■ Solubility(ies) SECTION 11: TOXICOLOGICAL INFORMATION

■ Initial boiling point an boiling range

■ Flash point T is section i entif es toxicological an health e ects in or-

■ Evaporation rate mation or in icates that such ata are not available. T e

■ Flammability (soli , gas) require in ormation consists o the ollowing:

■ Partition coe cient: n-octanol/water ■ In ormation on the likely routes o exposure (inhalation,

■ Auto-ignition temperature ingestion, skin an eye contact). T e SDS shoul in icate

■ Decomposition temperature i the in ormation is unknown.

■ Viscosity
■ Description o the elaye , imme iate, or chronic e ects

Te SDS may not contain every item on the above list rom short- an long-term exposure.

because in ormation may not be relevant or is not available. ■ T e numerical measures o toxicity (e.g., acute toxicity

When this occurs, a notation to that e ect must be ma e or estimates such as the LD50 [me ian lethal ose])—the

that chemical property. Manu acturers may also a other rel- estimate amount (o a substance) expecte to kill 50% o

evant properties, such as the ust e agration in ex (Kst) or test animals in a single ose.

combustible ust, use to evaluate a ust’s explosive potential. ■ Description o the symptoms. T is escription inclu es the
symptoms associate with exposure to the chemical inclu -

ing symptoms rom the lowest to the most severe exposure.
SECTION 10: STABILITY AND REACTIVITY ■ In ication o whether the chemical is liste in the National

oxicology Program (N P) Report on Carcinogens (latest
Tis section escribes the reactivity hazar s o the chemical e ition) or has been oun to be a potential carcinogen in

an the chemical stability in ormation. T is section is bro- the International Agency or Research on Cancer (IARC)

ken into three parts: reactivity, chemical stability, an other. Monographs (latest e itions) or oun to be a potential

T e require in ormation consists o the ollowing:
carcinogen by OSHA.

Reactivity

■ Description o the specif c test ata or the chemical(s). SECTION 12: ECOLOGICAL INFORMATION
T ese ata can be or a class or amily o the chemical i

such ata a equately represent the anticipate hazar o (NONMANDATORY)

the chemical(s), where available.
T is section provi es in ormation to evaluate the environ-
Chemical stability mental impact o the chemical(s) i it were release to the

environment. T e in ormation may inclu e
■ In ication o whether the chemical is stable or unstable
un er normal ambient temperature an con itions while ■ Data rom toxicity tests per orme on aquatic an /or ter-

in storage an being han le restrial organisms, where available (e.g., acute or chronic

■ Description o any stabilizers that may be nee e to main- aquatic toxicity ata or f sh, algae, crustaceans, an other
tain chemical stability plants; toxicity ata on bir s, bees, plants)