Page 132 - Clinical Hematology Atlas
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116 SECTION THREE ERYTHROCYTES
INCLUSIONS WITH SUPRAVITAL STAIN
Stained with New Methylene Blue
A B
FIGURE 12–5A Reticulocytes. FIGURE 12–5B Heinz bodies.
CELL: Anuclear immature erythrocyte CELL: Mature erythrocyte
COMPOSITION: Precipitated RNA COMPOSITION: Precipitated hemoglobin
NUMBER: $2 per cell NUMBER: Single or multiple, generally membrane-
COLOR: Dark blue bound
Associated with: Erythrocyte maturation COLOR: Dark blue to purple
NOTE: Supravital stains are taken up by living cells. Associated with: Unstable hemoglobin, some
hemoglobinopathies, some erythrocyte enzyme
deficiencies (e.g., glucose-6-phosphate
dehydrogenase)
FIGURE 12–5C Hemoglobin H. (From the American Society for Hematology slide bank.)
CELL: Mature erythrocyte
COMPOSITION: Hemoglobin b chains
NUMBER: Multiple evenly dispersed granules described as “golf balls” or “raspberries”
COLOR: Dark blue
