Page 136 - Clinical Hematology Atlas

120 SECTION THREE ERYTHROCYTES

MICROCYTIC/HYPOCHROMIC ANEMIA
Iron Deficiency Anemia

A B
FIGURE 13–1A Severe iron deficiency anemia FIGURE 13–1B Iron deficiency anemia (PB 31000).
(peripheral blood [PB] 3500).

Peripheral Blood: Erythrocytes are hypochromic
and microcytic; large variation in size; possible
thrombocytosis
NOTE: Small lymphocyte depicted for size
comparison.
Bone Marrow: Erythrocyte precursors are smaller
and more numerous than normal and have
shaggy cytoplasm. There is nuclear cytoplasmic
asynchrony, with cytoplasmic maturation lagging
behind that of the nucleus.

C
FIGURE 13–1C Iron deficiency anemia
(bone marrow [BM] 31000; showing shaggy
cytoplasm).

Although characteristic findings for disease states are listed, not all may be present in one patient.
The most common ones are depicted.