Page 81 - Clinical Hematology Atlas
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CHAPTER 6  MONOCYTE MATURATION    65

                                                   MONOCYTE

                                                              Cytoplasm










                                                                                           Nucleus


                                                                      Vacuoles
                                                            B
                                                               FIGURE 6–6B  Schematic of monocyte.
                    A
                         FIGURE 6–6A  Monocyte.


               SIZE:  12-20 mm
               NUCLEUS:  Variable; may be round, horseshoe
                  shaped, or kidney shaped; often has folds
                  producing “brainlike” convolutions
               Nucleoli:  Not visible
               Chromatin:  Lacy
               CYTOPLASM:  Blue-gray; may have pseudopods
               Granules:  Many fine granules frequently giving the
                  appearance of ground glass
               Vacuoles:  Absent to numerous
               N/C RATIO:  Variable
               REFERENCE INTERVAL:
               Bone Marrow:  2%
               Peripheral Blood:  3% to 11%
                                                           C
               Refer to Table 1-1 for more examples.
                                                           FIGURE 6–6C  Electron micrograph of
                                                           monocyte (316,500). Specimens for electron
                                                           microscopy are prepared by embedding tissue in
                                                           a suitable medium, such as resin. Ultra-thin cross-
                                                           sections are then prepared. Because this image
                                                           shows a cross-section, the lobes of the nucleus
                                                           appear to be separate, but they are not.
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