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             Financial support and conflicts of interest for all authors   ulent data or plagiarism, during or after the publication
             must be declared. Further information on this can be   process, they will be investigated by the editorial board,
             obtained from the International Committee for Medical   including contact with the author’s institution if necessary
             Journal Editors (http://www.icmje.org/).   so that a decision on the appropriate corrections, clarifi-
                                                        cations, or retractions can be made. The publisher agrees
             The reported research must be novel and authentic and   to publish this as necessary so as to maintain the integrity
             the authors should confirm that the same data has not   of the academic record.
             been and is not going to be submitted to another journal
             (unless already rejected). Statements made in the introduc-
             tion and discussion should be supported by appropriate   Protection for Research Participants
             references, and sufficient experimental detail should be pro-  These policies are in accordance with the recommenda-
             vided to allow for repetition of the study by another group.   tions of The International Committee of Medical Journal
             Plagiarism of the text/data will not be tolerated and could   Editors (ICMJE)
             result in retraction of an accepted article. Any text or fig-
             ures reproduced for another source require the permission   n  Humans
             of the original copyright holders (normally the publishers).  1.  If  experiments or research reported in the article
             Any manipulation of figures should be equally applied and   involve human subjects, the authors must indicate
             described in the text (including pseudocoloring) and must   if their procedures were approved by an Institu-
             not change the meaning of the figure.          tional Review Board, ethics committee, or similar
                                                            regulatory oversight committee. If a review board
             When humans, animals, or tissue derived from them have   or committee is not available, the authors should
             been used, then mention of the appropriate ethical approval   indicate that their procedures are in accordance
             must be included in the manuscript.            with the Helsinki Declaration as revised in 2013.
             Reviewer responsibilities: Reviewers are expected to   2.  Manuscripts must be accompanied by a statement
             not possess any conflicts of interest with the authors and   that the informed consent of research participants
             research. They should review the science objectively and   was obtained prior to participation or that docu-
             provide recommendations for improvements where nec-  mentation of informed consent was waived by the
             essary. When aware of relevant published work not being   Institutional Review Board, ethics committee, or
             cited, the reviewers should recommend inclusion of these   similar regulatory oversight committee.
             references. If the reviewer feels that they would be unable
             to repeat the study as described, then additional meth-  If images or other identifying information is included in
             odological details should be requested. Any unpublished   the manuscript, explicit written informed consent of the
             information read by a reviewer should be treated as con-  individual/patient must be obtained and included with
             fidential.                                 your submission. Measures to protect the confidentiality
                                                        of the individual(s) should also be employed. If consent
             Editorial responsibilities: The editors will select an appro-  cannot be obtained, you are encouraged to contact the edi-
             priate number of reviewers for the manuscript so that they   tor for further guidance.
             can make an informed decision about whether to reject/
             accept a manuscript. Their decision must be based only on   n  Animals
             the paper’s importance, originality, clarity, and suitability   If experiments or research reported in the article involve
             for the journal. They must not have a conflict of interest   animals, the authors must indicate if their procedures were
             with the authors or work described. The anonymity of the   performed in accordance with the U.S. Public Health Ser-
             reviewers must be maintained.
                                                        vice’s (PHS) Policy on Human Care and Use of Laboratory
             Should problems come to light after acceptance, then the   Animals and the Guide for the Care and Use of Laboratory
             editors agree to promote the publication of corrections   Animals and were approved by appropriate institutional
             and/or retractions as deemed necessary.    review committee(s).
             Publishing responsibilities: The publisher agrees to ensure   Editors reserve the right to reject manuscripts if there is
             that, to the best of their abilities, the information that they   doubt that appropriate ethical standards have not been
             publish is genuine and ethically sound. If publishing ethics   met in research involving human and animal subjects or
             issues come to light, not limited to accusations of fraud-  if there is reason to suspect research misconduct.
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