Page 13 - 10. Asthma
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STIMULI
CHEMICAL MEDIATOR RELEASE
Histamine, prostaglandins and leukotriene (inflammatory mediators) are
released by mast cells in the bronchial mucosa
BLOOD VESSELS BECOME EASY TO PERMEATE
Plasma easily penetrates blood vessels
BRONCHOSPASM INFLAMMATORY CELL
ACTIVATION
Mediators stimulate sympathetic
receptors and the smooth muscle Inflammatory media such as
of the bronchial wall causes eosinophils, neutrophils, and
bronchoconstriction basophils are released
.
