Page 34 - OCCUPATIONAL EXPOSURE GUIDELINE

01.FA 4/23/09 11:13 AM Page 27

APPENDIX 6c

DETERMINING THE NEED FOR HIV POST EXPOSURE PROPHYLAXIS (PEP)
AFTER AN OCCUPATIONAL EXPOSURE (continued)

STEP 3 : Determine the PEP Recommendation (Table 2 & 3)

Recommended HIV Post Exposure Prophylaxis (PEP) for mucous membranes exposures and
non-intact skin exposures (Table 2)

Source of
Exposure HIV Positive HIV Positive Unknown HIV Unknown HIV Negative
Type Class 1 Class 2 Source
Status

Small Consider Recommend Generally, Generally, No PEP is
Volume basic basic no PEP is no PEP is warranted
2-drug 2-drug warranted warranted
PEP1 PEP

Large Recommend Recommend Generally, no Generally, no No PEP is
PEP is
Volume basic expanded PEP is warranted; warranted 27
2-drug PEP >3-drug PEP warranted; however,
however, consider
consider basic 2-drug
basic 2-drug PEP in
PEP for settings in
which
source with exposure
HIV risk to HIV
factors infected
person is
likely

1. The recommendation to “consider PEP” indicates that PEP is optional; a decision to initiate
PEP should be based on a discussion between the exposed person and the treating clinician
regarding the risks versus benefits of PEP.

Guidelines On Occupational Exposures To Human Immunodeficiency
Virus (HIV), Hepatitis B Virus (HBV) And Hepatitis C Virus,
And Recommendations For Post Exposure Prophylaxis (PEP)