Page 24 - PULMONARY ARTERIAL HYPERTENSION
P. 24

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                Laboratory Investigation








                • A complete blood (CBC) count, biochemistry panel, prothrombin time (PT), and activated partial
                   thromboplastin time (aPTT)


                • Arterial blood gas determinations to assess for hypoxemia.




                • Collagen-vascular disease screening can be performed by measuring antinuclear antibody (ANA)
                   levels





                • Liver function tests, as well as markers of synthetic function (ie, albumin, international normalized
                   ratio [INR]), and platelet levels may indicate liver disease and/or portal hypertension.





                • In patients at risk for heritable pulmonary arterial hypertension (PAH), screening for gene
                   mutations such as BMPR2 also may be considered.





                • Iron studies - patients with idiopathic PAH (IPAH)
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