Page 608 - Ultimate Visual Dictionary (DK)
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THE MODERN WORLD
       Cloning technology                                                                  Spare cells from

                                                                                           egg development

       IN A LIVING CELL THE GENETIC MATERIAL DNA (deoxyribonucleic      NORMAL REPRODUCTION
       acid) contains thousands of units called genes that carry                      Nucleus with
                                                                                      mother’s
       instructions for development, growth, and repair of the living
                                                                                      genetic
       creature. During normal reproduction, half the mother’s genetic                material
       material contained in an egg cell joins with half the genetic
       material from the father carried in a sperm cell, to form a
       unique new genome (set of genes) for a new life. During the
       early stages of embryo development, the fertilized egg divides
                                                                 Egg cell            Egg cell
       into stem cells, which have the potential to become       membrane
       specialized into the hundreds of cell types in a                      Nucleus with
                                                                             mother’s
       body. Through therapeutic cloning, stem cells   THERAPEUTIC CLONING   genetic
       can be produced in a laboratory. It is hoped that                     material       Polar body
                                                                                            (spare genetic
       in the future this technology can be used to grow                                    material) forms
       new tissue that can be transplanted back into the   Egg                              as part of final
       donor to treat illness, without fear of rejection—  cell with                        egg cell division
                                                      polar body
       when the body recognizes a transplanted part
                                                                                    Fragments of DNA stain as
       as “foreign” because it has different genes, and   Zona                      dark “bar code” bands
       tries to destroy it. In another form of cloning,   pellucida
                                                       (outer casing
       performed experimentally using animals, genetic   of egg cell)
       material from a donor animal has been inserted
       into an egg from another animal that has                       “Plug” of
       been emptied of its own genetic                                zona
                                                                      removed
       material, to produce an
       animal genetically
       identical to the donor.

                        Suction through micro-                   Gentle suction   GEL IMAGE SHOWING DNA
                        pipette holds egg steady                 through micro-  PROFILE
                                                                 needle
                 Micro-needle                     Zona plug
                 inserted through egg             discarded                              Egg cell
                 cell membrane                                                           provides
                                                                                         conditions for
                                                          Polar body      Discarded      multiplication
                                                          removed         parts no
                                                                          longer
                                                                          needed
                                                   Egg genetic
                                                   material in
                                                   nucleus
        Zona (casing)  Egg cell
                                                   removed




                                                                                              Donor genetic
                                                                                              material
                                                                                              introduced
                                        Egg cell                                              into egg cell
                                        nucleus
                                        containing
                                        genetic                                  Stem cells
                                        material   “Enucleated” egg cell         (unspecialized or
                                                   (lacks nucleus with           undifferentiated cells)
        CENETIC MATERIAL REMOVED FROM EGG          genetic material)             collected from donor

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