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                                                         brains of the boys, but not the men, while there  by 7 percent, and folate linkked to a 20 percent
                                                         was no difference seen in the brain structures of  reduced risk of stroke.
                                                         the boys given a placebo.                       The only problem is that the studies
                                                                                                                             w
                                                         Radiology, 2019; 182528                      the researchers analyzed were limited
                                                                                                      to randomized controlled trials, many off
                                                         Blood pressure meds cause                    which came up with partial results, had
                                                         dangerous gut problem                        drug company funding or were designed
                                                                                                                              w
                                                         A common blood pressure drug can cause       without an adequate understanding
                                                                                                                                          h
                                                                                                                                          h
           Doctors prescribe opioids even                diverticulosis, a bowel problem that affects   nutrition. Plenty of indepenndent studies have
                                                                                                      reported benefits of taking vitamins.
                                                         many elderly people.
           to small children
                                                           Calcium-channel blockers are               Ann Intern Med, 2019; 171: 190–8
           Doctors are prescribing opioids—the powerful
                                                         antihypertensives—they keep high blood
           and highly addictive painkillers—to young     pressure under control—that also raise the risk  Antibiotics raisebbowel
           children. Around 60 percent of children who
                                                         of diverticulosis, a bowel problem that causes   cancer risk
           have their tonsils removed are being given the
                                                                                                                                     el
                                                         small bulges or pouches in the intestine.    Antibiotics increase the risk of bowel, ,
                                                                                                                              k
                                                                                                                                     el
                                                                                                                                      l
                                                                                                                                      l
           drugs, a new study has discovered.
                                                           Left untreated, diverticulosis can lead to   or colon, cancer. Nearly 72 percent t t t
              The children are being given an average of
                                                         diverticulitis, when the pouches become      of people with the cancer ad tak
           48 doses of opioids after a tonsillectomy, say
                                                         inflamed.                                     the drug within 10 years b fore th
           researchers at the University of Michigan, who
                                                           The problem affects around 65 percent of    were diagnosed, a new study has
           reviewed case records of 15,793 children who
                                                         people over 85. It can be life-threatening and   discovered.
           had the operation in a private clinic.
                                                                                                                              e
                                                         may need emergency treatment if the pouches     The drugs can double the risk for
              Some 60 percent of these children, who
                                                         burst or become infected.                    bowel cancer, although this varied
           were between one and 18 years old, were given
                                                           Calcium-channel blockers are the only      according to the length of time the
           opioids. The painkillers are thought to reduce
                                                         antihypertensives linked to diverticulosis, say   drugs were taken and their potency.
           complications after surgery, but the researchers
                                                                                                                              e
                                                         researchers from Imperial College London.       Other cancers of the digestive
           say there is no evidence the drugs are any more
                                                         They also tested ACE inhibitors and beta     system were also more likely after
           protective than standard NSAIDs (nonsteroidal
                                                         blockers by analyzing gene variants in around   taking antibiotics, but,paraadoxically,
           anti-inflammatory drugs) such as ibuprofen.
                                                         750,000 people.                              the risk of rectal cancer was s
              Constipation was more likely to occur among
                                                           The researchers aren’t sure why the drugs   reduced.This could be because the
           children taking opioids, the researchers found,
                                                         should cause diverticulosis but suspect they   rectum is at the end of the d digestive
           and in one case, the child became addicted.
                                                         could be affecting the ability of muscles in the   system, and the pattern of risk
              On average, each child was given an eight-day
                                                         intestine to push food through the gut.      seems to follow the way foo od travels
           prescription, equivalent to 48 doses—far more
                                                           Genetic variant testing is a relatively new   through the gut.
           than they should need, the researchers say. This
                                                         science that allows researchers to assess the   The cancer risk is increased because
           overprescribing could put the health of family
                                                         benefits and side-effects of drugs without     antibiotics cause dysbiosis, a disturbance of
           and friends at risk if they take the unused pills.
                                                         having to launch expensive, lengthy trials   the gut microbiome, the bo ody’s
           JAMA Otolaryngol Head Neck Surg. 2019 Aug 8
                                                         involving thousands of patients.             universe of bacteria, say
                                                         Circulation, 2019; 140: 270–9                researchers from Johns
           Ritalin changes children’s                                                                 Hopkins University School
           brain structure                               Why cheaper isn’t better when  of Medicine.
           ADHD (attention-deficit hyperactive disorder)   it comes to vitamins                           Using a database of 11.3
           drugs such as Ritalin alter the structure of
                                                         Buy high-quality vitamins—the inexpensive    million patient histories,
           children’s brains. They change the distribution
                                                         brands probably won’t do a thing for your    the researchers found near rly
           of white matter in the brain, which affects their
                                                         health, new research suggests.               29,000 cases of colorectal
           ability to learn—paradoxically, the very thing
                                                           The popular brands won’t help you live     cancer diagnosed between 1989 and 2012
           the drug is supposed to improve.
                                                         longer, and they don’t protect against heart   and compared their histories of antibiotic
              Profound changes to the brain were
                                                         disease, say researchers from Johns Hopkins   use against 137,000 health hy people.
           seen within four months of taking ADHD
                                                         School of Medicine, who took a second look at   Penicillin seemed to carry the greatest
           medication—and the researchers who made
                                                         277 clinical trials of popular vitamins, minerals   cancer risk.
           the discovery have urged doctors to prescribe
                                                         and nutritional supplements.                    Although doctors have been told to
           the drugs only when absolutely necessary.
                                                           They certainly won’t do you any harm, but   reduce antibiotic prescribin ng to slow the
              Researchers from the University of
                                                         with 52 percent of Americans taking at least   rise of antibiotic-resistant ‘s superbugs,’ the
           Amsterdam carried out MRI scans on the
                                                         one vitamin a day and spending a total of $31   fact that the drugs also raise the risk of colon
           brains of 50 boys and 48 men who had been
                                                         billion a year in the process, it might be hoped   cancer is another good reason why alternatives
           diagnosed with ADHD. Half the participants had
                                                         they’d do some good as well.                 need to be found, the resea archers say.
           been prescribed Ritalin (methylphenidate) and
                                                           Only omega-3 and folate supplements had       People are taking an ave erage of 10
           the rest were instead given a placebo.
                                                                                                                                        o
                                                                                                                                         a
                                                         any health benefits, the researchers found,   antibiotics each year, which h adds up to a
              After four months of taking the drug, the
                                                         with omega-3s reducing the risk of a heart   global annual total of 70 billion doses.
           researchers saw significant changes in the
                                                         attack by 8 percent and coronary heart disease  Gut,2019;pii:gutjnl-2019-318593
         FACEBOOK.COM/WDDTYAUNZ                                                                                                   ISSUE 04 | FEB/MAR 2020 | WDDTY 23
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