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                                                                                                                         T
                                                                  Three                                                  Three CT scans
                                                                                                                          k
                                                                  more                                                    kick-start
                                                                                                                          c
          Healthy                                                 countries s                                             cancer


                                                                                                                       CT (
                                                                                                                          computed tomography) is
                                                                                                                          c
                                                                  phase out                                           suppo
                                                                                                                          osed to be a safe screening
          lifestyle                                               dental                                              techn vered that the radiation from just
                                                                                                                           ology—but researchers have
                                                                                                                      discov
                                                                  amalgam m                                         cancero scans can prime cells to become
                                                                                                                     three
          trumps                                                  fillings                                      DNA  radiolo e CT radiation doesn’t damage
                                                                                                                          ous.
                                                                                                                     Becaus
                                                                                                               DNA, radiologists have been told the
                                                                                                               technology is safe—but instead the scans
                                                                  Three more European countries are
          genetic                                                 phasing out the use of amalgam—              alter healthy cells and make them “cancer-
                                                                                                               capable,” which means they make cancer
                                                                  which is 50 percent mercury—in dental
                                                                  practices. Ireland, Finland and Slovakia     more likely to develop.
                                                                                                                  Radiation from just three CT scans is
          riskof                                                  have announced a timetable that will see     enough to increase the risk, say researchers

                                                                  amalgam banned over the next few years.
                                                                                                               from the University of Cambridge, and
                                                                    They join Sweden and Norway in             creates mutations in cells—known as p53
          dementia                                                banning amalgam, which has been linked       mutations—that make them more likely to
                                                                  to neurological and kidney problems.
                                                                                                               become cancerous.
                                                                                                                  The researchers have examined the effects
                                                                    Dentists in all 27 member states of
                                                                  the European Union are forbidden from        of CT scans on cells in the esophagus—which
          Lifestyle can trump genetics—even when
                                                                  using the material in pregnant and           connects the throat to the stomach—of
          it comes to having an inherited biological                                                           laboratory mice. A radiation dose equivalent
          makeup that doubles the risk of dementia.               breastfeeding women and in children          to three scans started the spread of p53
             A healthy lifestyle—including a good                 under the age of 15.                         mutant cells until they overwhelmed the
          diet and not smoking—reduces the risk of                  Under the 2018 ruling, the member
                                                                                                               healthy cells, in what the researchers called
          dementia by around 30 percent in people                 states have also been asked to submit
                                                                                                               the body’s “Game of Clones.”
          who have a genetic predisposition to develop            plans for the phased withdrawal of              But taking an antioxidant before having
          the condition.                                          amalgamfromalldentalpractices.Ireland,       a scan seems to block any damage it may
             Healthy living has an even bigger                    Finland and Slovakia have been among the     cause. An over-the-counter antioxidant—the
          protective effect in people who don’t have
                                                                  first to respond.                             researchers used N-acetyl cysteine (NAC)—
          the ‘bad genes,’ which suggests the problem
                                                                    The ruling follows pressure from lobby     gives healthy cells the extra boost they need
          is avoidable for most people who live well,
                                                                  groups such as the Campaign for Mercury-     to ward off the mutations.
          say researchers from the University of Exeter
                                                                  Free Dentistry, which is now turning its     CellStemCell,2019;pii:S1934-5909(19)30275-9
          in the UK.
                                                                  focus to North America.
             They tracked the health of more than
                                                                    Although the American Dental
          196,000 people with an average age of 64,
          who weren’t showing any signs of dementia.              Association still supports the use of
             Of these, 20 percent had a higher risk of            amalgam, claiming it doesn’t have any
          developing the condition because of their               health risks, the campaign is confident the
          genetic profile—and 1.13 percent of those                US Food and Drug Administration (FDA)
          who followed a healthy lifestyle eventually             may soon shift its position.
          suffered from dementia compared to 1.78                    CampaignpresidentCharlesBrownsaid:
          percent who had an unhealthy diet and                   “Wecongratulatethesecountriesontaking
          didn’t exercise, suggesting lifestyle did have
                                                                  thisimportantsteptoprotectourplanet
          an impact on genes.
                                                                  andpatientsfromthisoutdatedmercury
             Just 0.5 percent of people with both a low
                                                                  product.NowtheheatisontheFDAand
          genetic risk and good lifestyle developed
                                                                  HealthCanadatogetoffthedime.”
          dementia.
                                                                    Regulators are concerned about any
             Ahealthylifestyle includesphysicalactivity,
          moderate alcohol drinking, a healthy diet               backlash to an outright ban. A sudden
          and not smoking, the researchers say.                   announcement that amalgam is unsafe
          JAMA,2019;322:430–7                                     could trigger millions of demands for
                                                                  the removal of dental fillings, and there
                                                                  is also the worry that people may sue
                                                                  the authorities if they link neurological
                                                                  problems to their fillings.


         FACEBOOK.COM/WDDTYAUNZ                                                                                                   ISSUE 04 | FEB/MAR 2020 | WDDTY 21
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