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4. Environmental Biotechnology, Forster, C. F and Waste, D.A. J. (1987) Ellis Horwood Halsted Press.

5. Biochemical Engineering Fundamentals 2nd Ed. Bailey, J. E. and Ollis, D. F. (1986) Mac Graw Hill,
New York.

REFERENCES

1. Stanier R.Y., Ingraham J.L., Wheelis M.L., Painter R.R., General Microbiology, Mcmillan
Publications, 1989.

2. New Processes of Waste water treatment and recovery. G.Mattock E.D. (1978) Ellis Horwood.

3. Environmental Biotechnology, Jogdand, S.N. (1995) Himalaya Publishing House, New Delhi.

OBT1706 FERMENTATION TECHNOLOGY L T P C
3 0 0 3
COURSE OBJECTIVES:

 To impart knowledge on design and operation of fermentation processes with all its
prerequisites.
 To learn the production of primary and secondary metabolites for various industrial
applications.
 To instruct the important concepts in fermentation engineering.

UNIT I OVERVIEW OF FERMENTATION PROCESSES 9

Basic configuration of fermentor and ancillaries, General requirements of fermentation processes, main
parameters to be monitored and controlled in fermentation processes. Methods of Fermentation: Batch,
Fed Batch and Continuous. Types of fermenters.

UNIT II RAW MATERIALS AND MEDIA DESIGN FOR FERMENTATION PROCESS
9

Criteria for good medium, medium requirements for fermentation processes, Types of medium, medium
formulation of optimal growth and product formation, design of various commercial media for
industrial fermentations, medium optimization methods.

UNIT III STERILIZATION KINETICS 6

Thermal death kinetics of microorganisms, heat sterilization of liquid media, filter sterilization of liquid
media, design of sterilization equipment- batch and continuous.

UNIT IV PRODUCTION OF PRIMARY AND SECONDARY METABOLITES 12

Product Recovery: Sedimentation, Centrifugation, Filtration, Precipitation, Chromatography, and
Crystallization. Organic feed stocks produced by Fermentation – Ethanol, Organic acids (Citric acid and
Lactic acid), Amino acids – L-Glutamic acid and Tryptophan. Mechanism of secondary metabolite
production,Antibiotics (Penicillin, Cephalosporin), Vitamins (Vitamin B12, Riboflavin).

Curriculum and Syllabus | Open Electives | R 2017 | REC Page 28