Page 38 - M.E. Medical Electronics Curriculum and Syllabus - R2019
P. 38

Department of BME, REC


               UNIT II        METALLIC AND CERAMIC BIOMATERIALS                                       9
               Introduction, Stainless steel, Cobalt-Chromium alloy, Titanium alloys, Titanium-Nickel alloys,
               Dental  metals,  Corrosion  of  metallic  implants,  Manufacturing  of  implants,  Nonabsorbable
               /relatively  bioinert  bioceramics,  biodegradable/resorbable  ceramics,  bioreactive  ceramics,
               deterioration of ceramics, bioceramic manufacturing techniques

               UNIT II        POLYMERIC AND COMPOSITE BIOMATERIALS                                    9
               Introduction, polymerization and basic structure, polymers used as biomaterials, sterilization,
               surface  modifications  to  for  improving  biocompatibility,  Structure,  bounds  on  properties,
               anisotropy  of  composites,  particulate  composites,  fibrous  composites,  porous  materials,
               biocompatibility and synthetic biodegradable polymers, collagen

               UNIT   IV      DEVELOPMENT AND PRESERVATION OF BIOMATERIALS                            9
               Development  of  functional  materials,  DNA  based  active  materials,  Phase  behavior,
               nonfreezing storage-hypothermic, freeze-thaw technology, freeze-drying, vitrification, Organ
               preservation and transportation.

               UNIT V         ARTIFICIAL TISSUE CREATION AND TESTING                           9
               Engineering  of  microvascular  prosthesis,  Testing  with  Tissue  Culture,  Testing  with  Soft
               Tissues and Testing at non Thrombogenic surface and implants of Biomaterial in Cardiac,
               Orthopaedics , Muscular and Ocular region.

                                                                                    TOTAL: 45 PERIODS
               OUTCOMES:
               On completion of the course the students will be able to
                   •  Identify the biomaterials for various biomedical applications.
                   •  Develop metallic and ceramic based biomaterials.
                   •  Improve biocompatibility.
                   •  Understand various preservation techniques for biomaterials.
                   •  Develop artificial tissues and the implants of biomaterials.

               REFERENCES:
                   1.  J.H.U.Brown (Ed), Advances in Bio Medical Engineering, Academic Press 1975.
                   2.  Rosario Pignatello, Biomaterials science and engineering, InTech, 2011
                   3.  Andrew F.VonRacum, Hand Book of Bio Medical Evaluation, Mc-Millan Publishers,
                       1980.
                   4.  Jacob Cline, Hand Book of Bio Medical Engineering, Academic Press in Sandiego,
                       1988.
                   5.  Jonathan  Black,  Biological  Performance  of  Materials-  Fundamentals  of  bio
                       compatibility, 4th Edition, CRC Press 2005.
                   6.  Larry  L.  Hench  and  Julian  R.Jones,  Biomaterials,  Artificial  organs  and  Tissue
                       Engineering, 2005.
                   7.  Buddy D.Ratner,Allan S .Hoffman, Frederick J. Schoen, Jack E. Lemons, Biomaterial
                   8.  Science;  An  Introduction  to  Materials  in  Medicine,2nd  Edition,  Elsevier  Academic
                       Press, San Diego,2004











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