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Cardio Diabetes Medicine 2017 547

GINGER: Basal Bolus provides superior glycemic
control vs. intensified premixed insulin therapy

Subjects:
• 310 with inadequately controlled type 2 diabetes (HbA 8–11%)
1c
• Pretreated with premixed insulin (mean of 5 years),
with some receiving metformin (continued during study)

Mean baseline values:
• HbA 1c (%): 8.5 Insulin glargine + three daily doses of insulin
• BMI (kg/m ): 30.1 glulisine +/- metformin (n=153)
2
• Diabetes duration (years): 13.0

Twice-daily premixed insulin +/- metformin (n=157)

Randomization 52 weeks

Fritsche A, et al. Diabetologia 2008;51 Suppl. 1:S83

GINGER: Basal Bolus provides superior glycemic

control vs. intensified premixed insulin therapy

Subjects:
• 310 with inadequately controlled type 2 diabetes (HbA 8–11%)
1c
• Pretreated with premixed insulin (mean of 5 years),
with some receiving metformin (continued during study)
Mean baseline values:
• HbA 1c (%): 8.5 Insulin glargine + three daily doses of insulin
• BMI (kg/m ): 30.1 glulisine +/- metformin (n=153)
2
• Diabetes duration (years): 13.0

Twice-daily premixed insulin +/- metformin (n=157)
Randomization 52 weeks

Fritsche A, et al. Diabetologia 2008;51 Suppl. 1:S83

Cardio Diabetes Medicine