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542 Initiation & Intensification of Insulin Therapy in T2DM

Factors determining the choice of insulin intensification regimen

Factor Premixed insulin Basal-bolus therapy
Patient preference for injection frequency Preference for fewer injections No problem with more injections
Frequency of self- monitoring blood glucose Unwilling to self monitor Willing to self monitor
Variability of lifestyle, including meal timing and Fixed daily routine Variable daily routine
carbohydrate content of meals
Presence of postprandial hyperglycaemia Less significant postprandial Significant postprandial hypergly-
hyperglycaemia caemia
Patient’s ability to follow prescribed regimen Limited cognitive function Motivated and good cognitive
function
Educational and emotional support Limited support Support available

Miami 4/12 rule

GCDC 2017