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                 Vascular endothelial growth factor   6p21.1  C936T / rs3025039   Higher risk                [54]
                 (VEGF)                                      rs2010963
                                                             rs699947
                 Cytochrome b-245 alpha chain   16q24.2      C242T                Higher risk                [54]
                 (CYBA)                                      rs4673
                 Heat shock protein        9q33.3            Promoter region      Higher risk                [55]
                 family A (Hsp70)                            57168556T>C
                 member 5 (HSPA5)                            rs391957
                 Adiponectin (ADIPOQ)      3q27.3            45T / G, rs2241766   Higher risk                [57,58]
                                                             276G/T rs1501299     Higher risk
                                            Table 1: Genetic factors and its variants associated with DPN

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