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638                      Cardio Diabetes Medicine 2017





                 Can The Projected World Center of Chronic Disease

                      Be Converted to The Worlds Control Centre of

                                               Chronic Disease?




                                          Dr.Alexander Thomas, President,AHPI

                                     Dr.V.C.Shanmuganandan, Joint Director,AHPI

                                            Dr.John Tharakan, Consultant,AHPI




              Introduction:                                      heart disease (IHD) and stroke constitute the major-
              The epidemiological transition in India in the past two   ity of CVD mortality in India (83%),  with IHD  being
                                                                             11
              decades has been dramatic; in a short timeframe, the   predominant.  The ratio of IHD to stroke mortality in
              predominant epidemiological  characteristics have   India is significantly higher than the global average,
              transitioned from infectious  diseases,  diseases  of   and is  comparable to that  of Western industrialized
              under nutrition, and maternal and childhood diseases   countries. Together, IHD and  stroke  are  responsible
              to non-communicable diseases (NCDs).  The disease   for  more  than  one-fifth (21.1%)  of  all  deaths and
                                                  8
              burden attributable to maternal disorders,  measles,   one-tenth  of the years  of life  lost in India (years
              protein-energy  malnutrition,  and diarrheal  diseases   of  life  lost  is  a measure  that  quantifies premature
              decreased  >50% in the past  2 decades, whereas    mortality by weighting younger  deaths more than
                                                                             8
              life  expectancy at birth increased  from 58.3 to 65.2   older  deaths).   The years  of life  lost  attributable to
              years, resulting in the ageing of the population during   CVD  in India increased by 59%  from 1990  to 2010
              the same  period.   Consequently, the NCD burden   (23.2 million to 37 million). 8
                              8
              increased rapidly in India, with a proportional rise in   In the  urban areas  of  India, the prevalence  of  dia-
              burden attributable to CVD. Nearly two-thirds of the   betes  mellitus has almost doubled in the past 20
                                       8
              burden of NCD mortality in India is currently      years,  from  9% to 17%, and in rural  areas  it has
                                                                                                 47
              contributed by CVD-related conditions. Despite wide   nearly quadrupled, from 2% to 9%. In 2013,  the  In-
                                                 9
              heterogeneity in the prevalence of risk factors across   ternational  Diabetes Federation estimated that
              different  regions (explained below), CVD is  the   65.1 million  people  in India had diabetes  mellitus,
              leading cause of death  in all parts of India,  includ-  a high proportion  of  whom were  adults of  working
                                                                    71
              ing  the poorer states and rural  areas.   The disease   age.   It is  estimated that  the  number of individuals
                                                 10
              transition in  India  in  the past  2  decades  resembles   with  diabetes mellitus will increase to an alarming
                                                                                    71
              the accelerated epidemiological transition model with   101 million by 2030.   An estimate based  on the
              a rapid shift to the age of delayed chronic diseases.  ICMR-INDIAB  study indicates  that  the number of
                                                                 individuals in India with prediabetes  (impaired  fast-
              According to the Global Burden of Disease  study   ing glucose or impaired  glucose tolerance)  is 77
              age-standardized  estimates  (2010),  nearly  a  quar-  million.   In addition,  based on epidemiological
                                                                       69
              ter  (24.8%)  of all deaths in India is  attributable  to   data  and conversion  rates among control  groups  in
                  11
              CVD   The age-standardized CVD death  rate of 272   intervention studies,  the conversion rate  from  pre-
              per  100 000  population in India is higher than  the   diabetes  to diabetes  mellitus  is  high. 72–74   Diabetes
              global average of 235 per 100 000 population .     awareness  and control are  poor  in rural  regions  in
              It is interesting to note that the public health strategy   comparison with urban regions. 69,70  Diabetes mellitus
              in  India  is  still  in  the process  of  making  this transi-  continues  to have  a positive  social gradient (with  a
              tion of addressing  NCDs. The health  infrastructure   higher burden among the rich and well educated), with
              in the  country which  has focussed on communica-  the exception of certain  settings such  as industrial
              ble  diseases  has not been recalibrated  to address   worksites. 66,75,76  However, a recently concluded study
              the increasing NCD burden in the country. Ischemic   on risk  factors of CVD in urban and  rural  Delhi
                                                                 suggests that there is no difference in the prevalence


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