Page 168 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003

A. Fractional excretion (FE) B. Tubular transport
Inulin
Substance X I
at the Nephron

1 2 3 4 Filtration

1
P In ,P X Active
1 – 2 – reabsorption
Concentrations of inulin and X rise due to H 2 O reabsorption H 2 O X X Reabsorption 2 3 4 2 3 4 Active Transport Processes
2
H 2 O
TF In ,TF X
Passive
reabsorption
or
secretion
of X
transcellular
Passive
5 5 secretion Plate 7.4
U In ,U X cellular
(U X /P X ) 6 6 secretion
FE X = Final urine Active
(U In /P In )
C. Overview of important transport processes along the nephron
Primary active Na + : Primary active
and passive Cl – : Secondary active
Secondary Na + NaCl
active Ca 2+ K +
H + K + 1 3
NH 3
5 6
1 3
1
Glucose, Na +
amino 2+ Na + : Primary active 3
acids, 1 Ca Cl – : Secondary active 1
phosphate, Cl –
lactate, 3 NaCl + H 2 O
sulfate 1 K
3 3
Secondary 4 2+ 6 H +
active Cl – Urea Metabolites, Ca 3
H 2 O drugs, Mg +
PAH +
1 Na
3 Cl –
Transport processes: see B.1–6
3 Urea
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