Page 172 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003

A. Reabsorption of glucose and amino acids B. Reabsorption of organic substances
Lumen Cell Blood

3
Filtered
Na
+
Glucose amount/time (mmol/min) 2 Maximum Glucosuria Excreted x a x ATP b Na x + Reabsorption of Organic Substances
glucose
reabsorption
Reabsorbed
glucose
rate
glucose
1
(GFR=120 mL/min) Na +
0 Brush border
0 10 20 30 40 membrane Basolateral
Plasma glucose membrane
Normal concentration (mmol/L) Glucose, Luminal
amino acids a Na + symport
(several systems), Plate 7.6
x phosphate,
C. Reabsorption of oligopeptides lactate, b Passive
sulfate, carrier transport
dicarboxylates
Dipeptides
D. Reabsorption of proteins by endocytosis
Oligopeptides
Albumin and
other proteins
1
Extracellular Receptor
peptidases recycling

a
Receptor
Reabsorbed as Endosome
free amino acids

Primary
Intracellular lysosome
H + peptidases
Secondary H +
2 lysosome
b
Lumen Cell Blood

a Na + symport carrier Amino
acids 159
b H + symport carrier
Lumen Proximal tubule cell Blood
Despopoulos, Color Atlas of Physiology © 2003 Thieme
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