Page 86 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003

A. ATP as a direct energy source
ADP P i Reserve enough for
10 contractions
Chemical
energy
Reserve: ATP ∆G ≈ –50 kJ/mol ATP Contraction
ca. 5 µmol Contraction
per g muscle
Mechanical
Heat + energy
B. Regeneration of ATP
1 Cleavage of creatine phosphate Energy Supply for Muscle
Reserve:
ca. 25 µmol CrP ADP
per g muscle Creatine
kinase
Short-term
Cr ATP peak performance
Plate 2.17
2 Anaerobic glycolysis
Reserve:
Glycogen ca. 100µmol/g muscle Blood Liver
glucose
Glucose-6-P 1
ATP
1
anaerobic Net gain: Long-term high
ATP
2 mol ATP/mol glucose
(3 mol ATP/mol glucose-6-P)
performance
4
ATP

Increase in lactic acid Drop in pH
–
2pyruvic acid 2pyruvate +2H + Broken down
+
2lactic acids 2H +2 lactate – in liver
and heart
3 Oxidation of glucose
Total net gain:
2
Acetyl-CoA 36 mol ATP/mol glucose
6O 2
aerobic H 2 O

Krebs 34
6CO 2 Endurance sport
cycle Respiratory ATP
chain 73

Despopoulos, Color Atlas of Physiology © 2003 Thieme
All rights reserved. Usage subject to terms and conditions of license.