Page 198 - AACN Essentials of Critical-Care Nursing Pocket Handbook, Second Edition
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N-acetyl procainamide is active metabolite;   hepatitis; rash QT prolongation; increased  Dosage adjustment should be made when   185




                   Comments  lupus-like syndrome; rash; agranulocytosis; QT prolongation Therapeutic range: PA 4-10 mg/L, NAPA   10-20 mg/L Diarrhea, nausea, headache dizziness;  hypersensitivity reactions including thrombocytopenia; hemolysis; fever  digoxin leve












                        Loading dose: (IV) 15 mg/kg at   25-50 mg/min  PO q12h
                   Dosage   Maintenance dose: (IV) 2-5 mg/min   Quinidine sulfate: 200-300 mg PO q6h Quinidine sulfate: 324-648 mg PO q8h  100-300 mg PO q6h; SR: 100-300 mg











                Antiarrhythmic Agents  Indications  Ventricular ectopy; conversion of atrial  fibrillation and atrial flutter; WPW  Ventricular ectopy; conversion of atrial  fibrillation and atrial flutter; WPW  Ventricular ectopy; conversion of atrial  fibrillation an













                   Agents  Procainamide              Disopyramide
                7.4   Class IA   Quinidine
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