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                                      C HAPTER 41 / Complementary and Alternative Approaches in Cardiovascular Disease  911
                   Treatments are designed to amplify the natural tendency of the  variables, such as blood pressure, heart rate, and peripheral vascu-
                   body to heal and eliminate toxins from the body.    lar resistance, often linked with cardiovascular problems. Medita-
                     Naturopathic remedies include  diet and clinical nutrition  tive techniques have been recommended to reduce heart rate,
                   counsel, particularly, use of naturally processed foods and herbs.  lower blood pressure, reduce body weight, or improve the lipid
                   Other therapies involve application of heat, water, air, or electric-  profile. However, it is not clear whether meditation has long-term
                   ity; physiotherapy, acupuncture, or manipulations; homeopathy;  effects on cardiovascular health. The Agency for Health Care Re-
                   and psychotherapy and counseling.                   search and Quality (AHRQ) published a comprehensive review of
                     Naturopathic physicians normally provide primary care and  817 studies of health applications of meditation published be-
                   do not perform major surgery, dispense pharmaceutical prescrip-  tween 1956 and 2005. 23
                   tions (other than botanicals or body-based substances), or use ra-  Evidence reviewed in the AHRQ summary suggests that med-
                   dioactive substances for diagnosis or treatment.    itation can evoke acute lowering of blood pressure in both healthy
                                                                       adults and in those with hypertension. Zen Buddhist meditation
                   Osteopathic Medicine                                (compared with a blood pressure monitoring group) was associ-
                                                                       ated with lowering diastolic blood pressure by approximately
                   Osteopathy was developed by Andrew Taylor Still, a physician who  6 mm Hg. Similarly, Transcendental Meditation was associated
                   became disillusioned with allopathic medicine after three of his  with small decreases in systolic (weighted mean difference 4.3 mm
                   children died in the meningitis epidemic of 1864. His goal was to  Hg) and diastolic (weighted mean difference 3.1 mm Hg) blood
                   establish practices to treat disease and promote health, rather than  pressure when compared to progressive muscle relaxation. Some
                   treat symptoms. He developed osteopathic manipulative treat-  mind-body interventions also involve energy medicine. Qi gong
                   ment and established his own medical schools. There are currently  involves breathing and movements which focus the mind and
                   about 20 schools of osteopathic medicine in the United States to-  move qi through channels or meridians in the body. In two trials,
                   day; their graduates become fully licensed physicians, Doctors of  hypertensive patients taught qi gong were compared with subjects
                   Osteopathy. Three principles guide osteopathy, as follows: (1) the  on a waiting list. The qi gong groups displayed a substantial re-
                   body is a unit designed to move, (2) structure and function are re-  duction in blood pressure (average systolic drop 17.8 mm Hg; di-
                   ciprocally interrelated by motion, and (3) the body possesses self-  astolic 12 mm Hg) compared to those waitlisted. Tai chi is an-
                   regulatory and self-healing mechanisms which are enhanced by  other form of focusing the mind and completing structured
                   the unrestricted motion of blood and body chemicals. 21  movements. Tai chi, yoga plus biofeedback, and yoga alone were
                                                                       each superior to no treatment or health education in decreasing
                                                                       systolic blood pressure; yoga alone and yoga plus biofeedback re-
                      MIND–BODY INTERVENTIONS                          duced diastolic blood pressure when compared with groups re-
                      FOR CARDIOVASCULAR HEALTH                        ceiving no treatment. 23
                                                                         Two trials reviewed in the AHRQ analysis (total of 99 partici-
                   There are several types of mind–body interventions used to im-  pants) demonstrated that tai chi was more effective than another
                   prove health. Some mind–body interventions are based on a be-  exercise in reducing resting heart rate. In two other studies, yoga
                   lief that the content of thoughts, beliefs, and emotions affects  was compared with lipid-lowering medications in reducing choles-
                   physical functioning; therapies are thought to improve health by  terol. One study followed patients for 4 months; the drugs were
                   evoking a more positive attitude. Other mind–body approaches  more effective than yoga in reducing total and low-density lipopro-
                   promote health by freeing the mind of troubling thoughts or by  tein (LDL) cholesterol. Another study followed patients for a year;
                   focusing thought so as to exclude usual mental patterns (e.g.,  the yoga and drug groups had similar reductions in cholesterol. 23
                   meditation or yoga; prayer, music, dance, or art therapy). Some  Meditation studies are difficult to compare. Studies vary in
                   mind–body therapies involve teaching the patient to control and  type and duration. Often the descriptions of the physical as-
                   regulate physical functioning and reduce stress responses (e.g.,  pects of the meditation techniques or training paradigms are
                   biofeedback).                                       incomplete, making it difficult to judge the integrity of the in-
                                                                       terventions. Another concern is the  lack of standards of
                   Meditation                                          dosage, including frequency or number of sessions to achieve
                                                                       desired results. It is difficult to judge if the intervention (med-
                   Meditation involves mental discipline, replacing typical thought  itation) is delivered as designed since it is an internal process.
                   patterns with a deeper state of relaxation or awareness. It has been  However, there are no documented adverse effects for medita-
                   a healing and/or spiritual practice in many cultures and religions  tion, thus the possibility of positive outcomes outweigh the
                   for more than 5,000 years. 22  Meditation goals sometimes include  risk of harm.
                   improved self-awareness, higher levels of consciousness, strength-
                   ened mental focus, or more relaxed frame of mind. 23  It often in-  Biofeedback
                   volves focusing, centering, and relaxing the mind and body by us-
                   ing techniques such as listening to the breath, repeating a phrase  Biofeedback methods are effective in acutely altering physiological
                   (called a mantra), avoiding thought, or focusing thought. Medita-a  parameters such as heart rate, blood pressure, body temperature,
                   tion usually involves focusing on the breath or using a specific  and heart rate variability (a measure of the variation in the beat to
                   breathing pattern. Generally, meditation practices require training  beat interval). Long-term effects are less well established. In one
                   to tame, quiet, or focus the mind and achieve a state of detached  randomized study of 38 hypertensive subjects, heart rate variability-
                   awareness. 23                                       based biofeedback in combination with emotional-response re-
                     Meditation has been employed in cardiovascular disease as   training to manage the stress response was associated with reduced
                   a method of regulating the stress response and physiological  blood pressure 3 months following training. 24
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