Page 103 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Pathophysiology of the Kidney (Overview)
RPF
Glomerular Reduced perfusion
damage
Bowman’s
capsule Artery
Tubular Glomerulus
damage Hormones
Distal
tubule
Hormones
Proximal GFR
tubule
Overview
Collecting duct

1 Urolithiasis
Metabolism Plate 5.1
Hormones
Gluconeogenesis
Fatty acid
breakdown
Loop of
Hormone Henle
inactivation
Urinary
Ammonia concentration
production
2
Hormone release 3 Excretion
Regulation Elimination
Erythropoietin Loss of useful Retention of useless
substances: or harmful
Calcitriol substances:
Renin, angiotensin H 2 O Glucose Uric acid
Kinins K + Amino acids Urea
Prostaglandins Na /Cl – Proteins Creatinine
+
+ –
H /HCO 3 VnO 4
2+ 2– Xenobiotics
Ca /HPO 4
Mg 2+ Uremia toxins

Erythropoiesis Water, electrolyte Blood pressure
and mineral balance 93

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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