Page 149 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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C.  Achalasia                  D.  Scleroderma
                           Swallowing
                                        Swallowing
                          mmHg                         Neuronal defects
                         40
                                       mmHg
                         0
                                      40
                         40
                                       0
                         0
                         40           40
        Swallowing       0             0
                               20s                    Muscle atrophia
                                      40
                       Excitation of the                no peristalsis
                       NCNA neurons    0              in smooth muscles
                  Distal                    20s                        Esophagus II
       40      esophagus                                Hypomotility
                       Sphincter pressure
        0              too high       Sphincter
        mmHg  Lower sphincter  Weight loss  pressure too low
       80              Trouble swallowing
                       Pain                                            Plate 6.3
       40
                Stomach
                        Esophagitis                   Gastroesophageal
        0
              20s          Pneumonia                    reflux disease
        E.  Gastroesophageal Reflux Disease
               Transient sphincter  Saliva production
                opening (air, CO 2 )  (in sleep, xerostomia)  Buffering capacity of saliva
                                                 (e.g. through smoking)
        Sphincter pressure   Abnormal peristalsis


                                 Volume     pH
                                clearance  clearance
       Phrenico-
       esophageal                                 Hiatus hernia
       ligament
                                                    Defective mucosal
                                                    protective mechanism
                                                    (e.g. alcohol)
       Diaphragm


                                Angle
                                of His
        Esophago-
        gastric                      Reflux esophagitis
        border
                                     Epithelial metaplasia
                          Reflux
                                          Carcinoma                   139
                           Photo in C.: Thurn P., et al. Einführung in die radiologische Diagnostik. 10th ed. Stuttgart: Thieme, 1998
                           Photo in E.: Treichel J. Doppelkontrastuntersuchung des Magens. 2nd ed. Stuttgart: Thieme; 1990
       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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