Page 153 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Gastritis
Autoantibodies
NSAIDs,
alcohol
IF
Multi-organ Parietal
cell
failure,
burns H + anhydrase
Carbonic
Trauma K +
Ischemia Helicobacter pylori Gastrin
infection H /K - + receptor
+
Lumen ATPase

Gastritis

Chronic active Plate 6.5
Erosive and antral gastritis
hemorrhagic (Type B) Atrophic fundal
gland gastritis
gastritis (Type A)
1 2 3
Gastrin
Acid secretion Pepsinogen
normal or
increased
Acid IF
secretion secretion
(Chronic)
gastric and
duodenal ulcer Gastrin Cobalamine
Acute ulcer absorption
4 G-cell Long-
term
hyperplasia
Reactive gastritis
ECL-cell Cobalamine
hyperplasia deficiency

Epithelial
metaplasia
Bleeding
Perforation Pernicious
anemia
Carcinoma Carcinoid 143

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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