Page 247 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Vascular Wall Changes on Atherosclerosis
                 Endothelium                      Necrotic nucleus
             Intima                   Fibrous cover plate  (foam cells, cell debris,
           Media                      (connective tissue,  cholesterol crystals)
                                      immigrant muscle cells)
       Adventitia         Endothelial damage
                          and dysfunction
                    Lumen
                                Foam cells
                                (lipid deposits)
                                in the intima
         1
         Normal
         vascular wall                                3
                        2                             Fibrous plaque   Atherosclerosis I
                                                      (atheroma)
                        Fatty streaks
        B.  Consequences of Atherosclerosis


                   Plaque                   Plaque                     Plate 7.32
              Residual                      enlargement
              lumen
                                                          Ischemia
                                                          (→infarction)
                                               Spasm


            Hypertension
                 Media damage
                             Nonatherosclerotic
                             causes
                                                         Thrombosis

              True aneurysm    Dissecting aneurysm
                                                         Embolism







                          Rupture                       Ischemia
                                                        (→infarction)


                 Thromboembolism
                                Rupture, occlusion of side branches, pericardial  237
                              tamponade, aortic regurgitation, thromboembolism

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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