Page 259 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

3-HMG-CoA-
reductase inhibitor
5
3-HMG- Cholesterol I + II
HDL receptor CoA-reductase synthesis
Liver cell
Cholesterol Metabolism
Polygenic hyper-
+ + cholesterolemia
Free
ACAT cholesterol
7
Familial Lipoprotein
dys-β-lipo- 13 Receptor
proteinemia Chol-E synthesis
Lysosome
Plate 8.3 + 8.4
Polygenic hyper-
cholesterolemia
Endocytosis
LDL receptor
Familial hyper-
cholesterolemia LDL
E (B100)
6 Endocrine
glands
LCAT
IDL HDL receptor
HDL
AI Steroid
CII hormones
Familial hyper- Hypo-α-
cholesterolemia 10 lipoproteinemia
E
B100
14
LDL
Chol receptor
LDL +Chol-E
Extrahepatic
8 cells
Scavenger
receptor
Atherosclerosis,
Skin Xanthoma esp. coronary 249
Macrophage heart disease

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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