Page 267 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Excess and Deficiency of Hormones as Disease-Producing System (Overview)
                                   2
        Regulating influences
                         Hypoplasia,     Hyperplasia,
                            aplasia      adenoma
            1

                                                    Ectopic
                                                    hormone production
                                                         3             General Pathophysiology of Hormones



                          Hormon-producing
                           glandular cell
                                            5
                      4           Hormone synthesis,
                    Receptors:          intracellular
                   density, affinity     transport,
                                                                       Plate 9.1
                                          release
                              Increased hormonal effect
            Feedback          Decreased hormonal effect  Hormone concentration
              6                                      7
                                    Binding to
                                 plasma proteins
                                                        Breakdown

                                    Receptors:
                  Intracellular   density, affinity
                  transmission                        Conversion
                                                     8


                 9



                                      Target
                                      cell
                           Cell function



           Hormonal effect
                            Clinical features of endocrinal disease   257


       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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