Page 269 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Abnormalities of Simple Endocrinal Regulatory Circuit

Glucose Glucose
Glycolysis
etc. Negative
feedback
Liver Hyperglycemia
Insulin Beta-cell
Insulin insufficiency Circuit
1 Pancreas
Normal regulation 3
Defect in hormonal gland
Glucose Endocrinal Regulatory
Amino Glucose
acids
Enzyme
defect Hypoglycemia Liver Hyperglycemia
insufficiency
Insulin
Insulin
2 Plate 9.2
Increased secretion in the 4
intertwined regulatory circuit Target organ defective
B. Abnormalities of Hypothalamus-Regulated Hormones
Hypothalamus
1
Liberin CRH
(CRH)
Pituitary
gland
Tropin Effect ACTH Effect
(ACTH) primarily
raised
3
Hormone
(cortisol) Cortisol
Adrenal CRH CRH
cortex primarily
raised
Normal regulation
2
ACTH Effect
ACTH Effect
4
Cortisol Cortisol Cortisol
primarily
raised
259

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
All rights reserved. Usage subject to terms and conditions of license.