Page 281 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Effects and Symptoms of  Adrenocortical Hormone Deficiency
                                                Decreased gluconeogenesis
                                             Increased glycolysis
         Proopiomelanocortin
                                                  1
         ACTH       3                                Hypoglycemia

             MSH
                                     Insulin
                                                     Epinephrine
          Melanotropic effect
          Brown discolor-        Sweating
          ation of the skin                  2
                                                Lipolysis              Addison’s Disease

                                         Protein
                                       breakdown             Tachy-
                                                             cardia
                                     Muscle weakness
                                                                       Plate 9.8
                                        Weight loss
                                           +
                                      Renal Na  retention
                4                                Na +

         Anemia,                        H +
         neutropenia,                   K +                Blood
                                                           pressure
         eosinophilia,                  Mg 2+
         thrombopenia,
         lymphocytosis                        Hypotonic
                                     5        dehydration

         Hydrochloric                 Acidosis,        GFR
         acid                         hyperkalemia,
                6                     hypermagnesemia   Reduced
                                                        catecholamine
          Gastrointestinal                              sensitivity
          infections
                                             Electrolyte disturbances



                 7                       Abnormal action
                                         potential generation
                                         and conduction
        Androgen deficiency              in the heart
               Pubic hair                        8
                                  Neuromuscular
                                  excitability                        271

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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