Page 283 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Androgen Excess and Deficiency
                              Gonadoliberin     Cachexia,
                               (GnRH)           damage to hypothalamus,
                                                genetic defects
                       Prolactin
                                           Persistently increased
                                           GnRH analogues
                       1
                                     Damage to pituitary               Deficiency

                     Lutropin  Follitropin
                      (LH)      (FSH)                                  and
                Leydig                                Sertoli cells
                                                      of the
                cells                                 seminiferous
                                                      tubules          Androgen Excess
                    Testosterone
                                    3        Inhibin
                                                     Spermiogenesis
                                           ABP
         Tumors       Blut
                2
         Adreno-
         genital        Testosterone  Testicular damage,  Lumen        Plate 9.9
         syndrome                      genetic damage
                  Iatrogenic                     Receptor defect
                  supply
                            DHT
              Reductase deficiency
                            Penis,
                           scrotum,
                          seminiferous
                           tubules                           Receding
                               Prostate,                     forehead
                               seminal
                               vesicles                      Growth of
                                                               beard
       Female voice                                         Male voice
                                 Libido and
                               aggressive behavior
       Absence of
       male hair                 Bone growth                  Hair on
                               Electrolyte retention           chest
                                Epiphyseal fusion
                                Protein synthesis           Amenorrhea
       Feminine
       fat                      Muscle growth
       distribution             Erythropoiesis
                                                             Rhomboid
                                Skin thickness               pubic hair
                               Sebaceous glands
       Hypotrophic
       genitalia                   HDL                         Hyper-
                                                              trophic
              Feminization of the male  Infertility  Masculinization of the female  clitoris  273
              due to testosterone deficiency  due to testosterone excess
       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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