Page 325 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

C. Chorea

Genetic defect Sydenham’s chorea
Rheumatic fever

Deposition of
immune complexes

2 Basal Ganglia II
Reversible
Glutamate cell damage Involuntary
movements
Glutamate action
Chorea the
Thalamus of
Diseases
2+
Ca inflow
Irreversible
degeneration
Ca 2+ Pallidum Substantia Plate 10.9
nigra
1 Huntington’s chorea Striatum

D. Hemiballism and Tardive Dyskinesia
Treatment with
neuroleptics
Ischemia,
tumor
Flinging movements Receptor density Dopamine
Hemiballism
Dopaminergic
Cell death in the overstimulation
subthalamic nucleus
Thalamus Involuntary movements
Tardive dyskinesia

Substantia
Pallidum nigra
1

2 Dopamine 315

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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