Page 323 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Basal Ganglia
Cortex

Striatum
Globus
pallidus Thalamus Basal Ganglia I

Subthalamic
nucleus
Cerebellum reticulata Transmitter: the
outer Glutamate of
inner compacta Acetylcholine
Substantia
nigra Dopamine Diseases
To brain stem GABA
and spinal cord
B. Parkinson’s Disease Plate 10.8
Genetic defect
Striatum
Thalamus Trauma,
inflammation,
reduced
perfusion,
poisoning
L-Dopa

Cell death in Dopa
substantia nigra
Am- MAO
1 phetamine Dopamine inhibitor
Dopamine deficiency
MAO

Facial
rigidity Break-
down
Rigidity Salivary flow,
sweating Dopamine
Tremor at rest Depression agonists
(not constantly)
Quiet, monotonous
Hypokinesia speech
Bent posture
2
Parkinson’s disease
3 Treatment
313
Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
All rights reserved. Usage subject to terms and conditions of license.