Page 81 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Development of Diffusion Abnormalities

[O 2 ] blood P O 2 capillaries [O 2 ] blood O 2 ven.

O 2 art. Contact time
P O 2 cap. P O 2 cap.
P O 2 alv.
[O 2 ] art. [O 2 ] ven. Abnormalities

P O 2 cap.
Work
Lung resection, Edema, Diffusion
emphysema, inflammation,
tuberculosis, etc. vessel dilation
F d K CO
Diffusion area Diffusion distance Permeability Cardiac output Plate 4.3
K· F Diffusion abnormality [O 2 ] ven.– [O 2 ] art.
d· CO P O2 cap.– P O2 alv.
B. Abnormal Diffusion: Concentrations of CO 2 and HbO 2 in Blood

Venous Arterial
blood 5 blood 5
7 6 13 13 5 4 6.5 13 6 5.5

1 2
Normal diffusion capacity Diffusion abnormality

[CO 2 ] blood [HbO 2 ] blood

Normal Normal

P CO 2 blood P O 2 blood
3 5
5 6 17 10 4 7 6.5 30 24 5.5

P O 2 (kPa)
3 4
P CO 2 (kPa) Abnormal diffusion with hyperventilation Abnormal diffusion with O 2 ventilation 71

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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