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CEREBRAL ISCHEMIA  n  43



             status  refers  to  the  amount  of  information   the complexities of the phenomenon, to test
             (variances  and  covariances)  available  com-  theoretical  models  specifying  causal  flow,
             pared  with  the  number  of  parameters  that   and  to  separate  the  effects  of  one  variable   C
             are to be estimated. If the amount of infor-  on  another  into  direct  and  indirect  effects.
             mation equals the number of parameters to   Although  causal  modeling  cannot  be  used
             be estimated, the model is “just identified.” If   to establish causality, it provides information
             the amount of information exceeds the num-  on the strength and direction of the hypoth-
             ber of parameters to be estimated, the model   esized effects. Thus, causal modeling enables
             is  “overidentified.”  In  both  cases,  a  unique   investigators to explore the process by which
             solution  for  the  parameters  can  be  found.   one variable might affect another and to iden-
             With the use of standard conventions, recur-  tify possible points for intervention.
             sive models are almost always overidentified.
             When the amount of information is less than                   JoAnne M. Youngblut
             the  number  of  parameters  to  be  estimated,
             the model is “underidentified” or “unidenti-
             fied,” and a unique solution is not possible.
             nonrecursive  models  are  underidentified      Cerebral isCheMia
             unless instrumental latent variables (a latent
             variable for each path that has a direct effect
             on one of the two latent variables in the recip-  Cerebral  ischemia  is  defined  as   inadequate
             rocal causation relationship but only an indi-  blood  flow  to  the  brain  to  meet  meta-
             rect effect on the other latent variable) can be   bolic  and  nutritive  needs  of  the  brain  tis-
             specified.                               sue  (Edvinsson,  MacKenzie,  &  McCulloch,
                 Causal  models  can  be  analyzed  with   1993).  The  severity  of  ischemia  depends  on
             standard  multiple  regression  procedures  or   the severity and duration of the reduction in
             structural  equation  analysis  programs,  such   cerebral blood flow (CBF) adversely affecting
             as  LISREL  or  EQS  (see  Structural  Equation   various  functional  and  metabolic  processes
             Modeling).  Multiple  regression  is  appropriate   as CBF decreases (Heiss & Rosner, 1983). The
             when each concept is measured with only one   brain stores no oxygen and little glucose and
             empirical  indicator.  Path  coefficients  (stan-  is  thus  dependent  on  a  constant  supply  of
             dardized  regression  coefficients,  β  )  are  esti-  oxygen and glucose from the blood.
             mated by regressing each endogenous variable   Cerebral  ischemia  may  be  focal  or
             on the variables that are hypothesized to have   global, depending on whether a part of the
             a direct effect on it. The fit of the model is cal-  brain  or  the  entire  brain  is  ischemic.  Focal
             culated by comparing total possible explained   cerebral ischemia occurs when a major cere-
             variance  for  the  just  identified  model  with   bral artery becomes occluded or constricted
             the total explained variance of the proposed   from  arterial  spasm,  emboli,  or  thrombo-
             overidentified  model.  Data  requirements  for   sis. Global ischemia occurs from an overall
             path analysis are the same as those for mul-  decrease  in  CBF,  for  example,  after  cardiac
             tiple  regression:  (a)  interval  or  near-interval   arrest.  Global  oxygen  deprivation  of  the
             data for the dependent measure; (b) interval,   brain may also occur as a result of asphyxia,
             near-interval, or dummy-coded, effect-coded,   anemia, hypoxia, or near drowning. nurses
             or orthogonally coded categorical data for the   are  responsible  for  identifying  individuals
             independent  measures;  and  (c)  5  to  10  cases   at risk for focal or global cerebral ischemia.
             per  independent  variable.  Assumptions  of   nursing  assessment  of  early  symptoms  of
             multiple regression must be met.         cerebral ischemia can allow for intervention
                 In  summary,  causal  modeling  tech-  and minimize the probability of permanent
             niques provide a way to more fully represent   damage.
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