Page 2091 - Hematology_ Basic Principles and Practice ( PDFDrive )

1856.e4 Part XII Hemostasis and Thrombosis

163. Scehnet JS, Jiang W, Kumar SR, et al: Inhibition of Dll4 mediated 190. Gale NW, Thurston G, Hackett SF, et al: Angiopoietin-2 is required
signaling induces proliferation of immature vessels and results in poor for postnatal angiogenesis and lymphatic patterning, and only the latter
tissue perfusion. Blood 109:4753, 2007. role is rescued by Angiopoietin-1. Dev Cell 3:411, 2002.
164. Lobov IB, Renard RA, Papadopoulos N, et al: Delta-like ligand 4 (Dll4) 191. Huang XZ, Wu JF, Ferrando R, et al: Fatal bilateral chylothorax in mice
is induced by VEGF as a negative regulator of angiogenic sprouting. lacking the integrin alpha9beta1. Mol Cell Biol 20:5208, 2000.
Proc Natl Acad Sci USA 104:3219, 2007. 192. Deryugina EI, Muller-Sieburg CE: Stromal cells in long-term cultures:
165. Rak J, Milsom C, May L, et al: Tissue factor in cancer and angiogenesis: keys to the elucidation of hematopoietic development? Crit Rev
the molecular link between genetic tumor progression, tumor neovas- Immunol 13:115, 1993.
cularization, and cancer coagulopathy. Semin Thromb Hemost 32:54, 193. Rafii S, Mohle R, Shapiro F, et al: Regulation of hematopoiesis by
2006. microvascular endothelium. Leuk Lymphoma 27:375, 1997.
166. Connolly AJ, Ishihara H, Kahn ML, et al: Role of the thrombin recep- 194. Yin T, Li L: The stem cell niches in bone. J Clin Invest 116:1195, 2006.
tor in development and evidence for a second receptor. Nature 381:516, 195. Kopp HG, Avecilla ST, Hooper AT, et al: The bone marrow vascular
1996. niche: home of HSC differentiation and mobilization. Physiology
167. Maragoudakis ME, Tsopanoglou NE, Andriopoulou P: Mechanism of (Bethesda) 20:349, 2005.
thrombin-induced angiogenesis. Biochem Soc Trans 30:173, 2002. 196. Butler JM, Nolan DJ, Vertes EL, et al: Endothelial cells are essential for
168. Nierodzik ML, Karpatkin S: Thrombin induces tumor growth, metas- the self-renewal and repopulation of notch-dependent hematopoietic
tasis, and angiogenesis: Evidence for a thrombin-regulated dormant stem cells. Cell Stem Cell 6:251, 2010.
tumor phenotype. Cancer Cell 10:355, 2006. 197. Sitnicka E, Wang QR, Tsai S, et al: Support versus inhibition of hema-
169. Suzuki K, Hayashi T: Protein C and its inhibitor in malignancy. Semin topoiesis by two characterized stromal cell types. Stem Cells 13:655,
Thromb Haemost 33:667, 2007. 1995.
170. Ushiba M, Okajima K, Oike Y, et al: Activated protein C induces 198. Sugiyama T, Kohara H, Noda M, et al: Maintenance of the hematopoi-
endothelial cell proliferation by mitogen-activated protein kinase activa- etic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone
tion in vitro and angiogenesis in vivo. Circ Res 95:34, 2004. marrow stromal cell niches. Immunity 25:977, 2006.
171. Petralia GA, Lemoine NR, Kakkar AK: Mechanisms of disease: the 199. Bussolino F, Bocchietto E, Silvagno F, et al: Actions of molecules which
impact of antithrombotic therapy in cancer patients. Nat Clin Pract regulate hemopoiesis on endothelial cells: memoirs of common ances-
Oncol 2:356, 2005. tors? Pathol Res Pract 190:834, 1994.
172. Kragh M, Loechel F: Non-anti-coagulant heparins: a promising 200. Broudy VC, Kovach NL, Bennett LG, et al: Human umbilical vein
approach for prevention of tumor metastasis (review). Int J Oncol endothelial cells display high-affinity c-kit receptors and produce a
27:1159, 2005. soluble form of the c-kit receptor. Blood 83:2145, 1994.
173. Browder T, Folkman J, Pirie-Shepherd S: The hemostatic system as a 201. Methia N, Louache F, Vainchenker W, et al: Oligodeoxynucleotides
regulator of angiogenesis. J Biol Chem 275:1521, 2000. antisense to the proto-oncogene c-mpl specifically inhibit in vitro
174. Guo N, Krutzsch HC, Inman JK, et al: Thrombospondin 1 and type megakaryocytopoiesis. Blood 82:1395, 1993.
I repeat peptides of thrombospondin 1 specifically induce apoptosis of 202. Bazzoni G, Dejana E: Pores in the sieve and channels in the wall: control
endothelial cells. Cancer Res 57:1735, 1997. of paracellular permeability by junctional proteins in endothelial cells.
175. O’Reilly MS, Boehm T, Shing Y, et al: Endostatin: an endogenous Microcirculation 8:143, 2001.
inhibitor of angiogenesis and tumor growth. Cell 88:277, 1997. 203. Rippe B, Haraldsson B: Transport of macromolecules across microvas-
176. Kerbel R, Folkman J: Clinical translation of angiogenesis inhibitors. cular walls: the two-pore theory. Physiol Rev 74:163, 1994.
Nat Rev Cancer 2:727, 2002. 204. Michel CC: Transport of macromolecules through microvascular walls.
177. Shih T, Lindley C: Bevacizumab: an angiogenesis inhibitor for the Cardiovasc Res 32:644, 1996.
treatment of solid malignancies. Clin Ther 28:1779, 2006. 205. Mehta D, Malik AB: Signaling mechanisms regulating endothelial
178. Herbst RS: Therapeutic options to target angiogenesis in human permeability. Physiol Rev 86:279, 2006.
malignancies. Expert Opin Emerg Drugs 11:635, 2006. 206. Anderson RG: Caveolae: where incoming and outgoing messengers
179. Lin MI, Sessa WC: Vascular endothelial growth factor signaling to meet. Proc Natl Acad Sci USA 90:10909, 1993.
endothelial nitric oxide synthase: more than a FLeeTing moment. Circ 207. Dvorak AM, Feng D: The vesiculo-vacuolar organelle (VVO). A new
Res 99:666, 2006. endothelial cell permeability organelle. J Histochem Cytochem 49:419,
180. Bombeli T, Karsan A, Tait JF, et al: Apoptotic vascular endothelial cells 2001.
become procoagulant. Blood 89:2429, 1997. 208. Siflinger-Birnboim A, Malik AB: Regulation of endothelial perme-
181. Bombeli T, Schwartz BR, Harlan JM: Endothelial cells undergoing ability by second messengers. New Horiz 4:87, 1996.
apoptosis become proadhesive for nonactivated platelets. Blood 93:3831, 209. Gautam N, Olofsson AM, Herwald H, et al: Heparin-binding protein
1999. (HBP/CAP37): A missing link in neutrophil-evoked alteration of
182. Schwartz BR, Karsan A, Bombeli T, et al: A novel beta 1 integrin- vascular permeability. Nat Med 7:1123, 2001.
dependent mechanism of leukocyte adherence to apoptotic cells. J 210. Garcia JG, Verin AD, Schaphorst KL: Regulation of thrombin-mediated
Immunol 162:4842, 1999. endothelial cell contraction and permeability. Semin Thromb Hemost
183. Gasparini G: Metronomic scheduling: the future of chemotherapy? 22:309, 1996.
Lancet Oncol 2:733, 2001. 211. van Hinsbergh WM: Endothelial permeability for macromolecules.
184. Herzog S, Sager H, Khmelevski E, et al: Collateral arteries grow from Mechanistic aspects of pathophysiological modulation. Arterioscler
preexisting anastomoses in the rat hindlimb. Am J Physiol Heart Circ Thromb Vasc Biol 17:1018, 1997.
Physiol 283:H2012, 2002. 212. Lonigro AJ, McMurdo L, Stephenson AH, et al: Hypotheses regarding
185. Helisch A, Schaper W: Arteriogenesis: the development and growth of the role of pericytes in regulating movement of fluid, nutrients, and
collateral arteries. Microcirculation 10:83, 2003. hormones across the microcirculatory endothelial barrier. Diabetes
186. Heil M, Eitenmuller I, Schmitz-Rixen T, et al: Arteriogenesis versus S38:1996.
angiogenesis: similarities and differences. J Cell Mol Med 10:45, 213. Bombeli T, Mueller M, Haeberli A: Anticoagulant properties of the
2006. vascular endothelium. Thromb Haemost 77:408, 1997.
187. Alitalo K, Tammela T, Petrova TV: Lymphangiogenesis in development 214. Gross PL, Aird WC: The endothelium and thrombosis. Semin Thromb
and human disease. Nature 438:946, 2005. Hemost 26:463, 2000.
188. Schneider M, Othman-Hassan K, Christ B, et al: Lymphangioblasts in 215. van Hinsbergh VW: The endothelium: vascular control of haemostasis.
the avian wing bud. Dev Dyn 216:311, 1999. Eur J Obstet Gynecol Reprod Biol 95:198, 2001.
189. Wigle JT, Harvey N, Detmar M, et al: An essential role for Prox1 in 216. Jin RC, Voetsch B, Loscalzo J: Endogenous mechanisms of inhibition
the induction of the lymphatic endothelial cell phenotype. EMBO J of platelet function. Microcirculation 12:247, 2005.
21:1505, 2002. 217. Aird WC: Coagulation. Crit Care Med 33:S485, 2005.