Page 2455 - Williams Hematology ( PDFDrive )

2426 Index Index 2427

Endocrine disorders Endothelins, 1968t Eosinophilorrachia, 960
anemia in, 553, 559–561 Endothelium-derived relaxing factor (EDRF). Eosinophil peroxidase, 929, 948, 952
in Langerhans cell histiocytosis, 1104– See Nitric oxide (NO) Eosinophils
1105 Endotoxin, 294. See also Lipopolysaccharide in asthma, 954, 955t
polycythemia and, 872, 879 (LPS) in chronic inflammation, 291
primary lymphomas, 1583 Endotoxin tolerance, 298 in chronic myelogenous leukemia, 1445
Endocytosis Energy clutch, 692 development, 926f
of extracellular heme and hemoglobin, Energy metabolism, regulation by hypoxia, disorders, 953–960
499, 500f 504f animal models, 951
pathways, 1061, 1062f Enhancer of zest homologue 2 (EZH2), 170 eosinophilia. See Eosinophilia
of transferrin, 622–623, 623f Enhancer of zest homologue 2 (EZH2) hypereosinophilia. See
Endogenous erythroid colonies (EEC), 1292 inhibitors, 337–338 Hypereosinophilic syndromes
Endogenous pyrogen. See Interleukin (IL)-1β Enolase, 692t, 695–696, 701t functions, 952–953, 954
Endoglin, 801–802, 1449 eNOS (endothelial nitric oxide synthase), eosinophilic granule proteins, 952–953
Endoglycan, 68 2283f, 2285 immunoregulation, 952
Endokinins A and B, 1878 Enoxaparin, 2274t, 2295 inactivation of helminths, 952
Endomitosis, 1816–1817, 1816f, 1817–1818 Enterococcus faecium, 2340 mediator release, 952
Endomucin, 68 Enterococcus infections, 383, 385. See also in gastrointestinal disease, 956
Endomyocardial biopsy, 1778, 1778f Bacterial infections granules, 928–929, 929f, 931, 931f
Endoplasmic reticulum, 204f, 205, 1171 Enteropathy-associated T-cell lymphoma heterogeneity, 950
Endoplasmic reticulum-Golgi intermediate (EATL), 1694t, 1695t, 1699–1700 hypodense, 950
compartment protein (ERGIC)-53, Entinostat inflammation and, 279
1171 for breast cancer, 240 measurement in blood, 953–954
Endothelial cells for myelodysplastic syndromes, 1361 in newborn, 105t
antiphospholipid antibodies and, Enzyme replacement therapy, for Gaucher in parasitic disease, 952, 956–957, 957t
2236–2237 disease, 1127–1128, 1128f production, 949–950
on blood/marrow films, 22f, 23 Enzymes receptors, 948–949, 949t
in coagulation, 1941, 1941f erythrocyte, disorders of. See Erythrocyte reference ranges in children, 15t
in disseminated intravascular coagulation, enzyme disorders secretion and activation, 953
2200, 2200f folate-dependent, 584–585 in skin conditions, 954, 955t
fibrinolytic proteins production by, in heme biosynthesis, 891f, 893f structure, 20f, 23, 928–929, 931, 931f,
1973–1974, 1973f leukocyte, 1049t 947–948, 948f
heterogeneity, 1967 lymphocyte membrane, 1143–1144, 1144t trafficking and tissue accumulation,
leukocyte interactions with, 1977–1978, macrophage, 1066t 950–951
1977t, 1979 neutrophil granules, 930t Eosinophiluria, 960
marrow, 56–57 in neutrophils, 933t Eotaxin, 291, 950
platelet interactions with, 1969f, Eosinophil cationic protein (ECP), 929, 931, EP300, 1644
1978–1979 953 EPAS1, 875, 878, 880
thromboregulatory molecules production Eosinophil-derived neurotoxin (EDN), 931, EPCR. See Endothelial protein C receptor
by, 1967–1968, 1968f, 1968t 953 (EPCR)
von Willebrand factor in, 1969f Eosinophil granules, 20f, 952–953 EPCs (endothelial progenitor cells), 2285
Endothelial dysfunction. See Atherosclerosis, Eosinophilia EPCs (epithelial progenitor cells), 450, 451
endothelial dysfunction in in asthma, 954, 955t Eph kinases, 1871–1872
Endothelial nitric oxide synthase (eNOS), causes, 954, 955–956t Ephrin ligands, 1871–1872
2283f, 2285 in chronic eosinophilic leukemia, 1469 Epidermal growth factor (EGF), 1848
Endothelial progenitor cells (EPCs), 2285 consultative approach to, 44 Epidermal growth factor-seven
Endothelial protein C receptor (EPCR), differential diagnosis, 1470 transmembrane (EGF-TM7), 1059
1953–1954 in gastrointestinal disorders, 955t, 956 Epidermodysplasia verruciformis, 1230
activated protein C and, 1972 in parasitic disease, 956–957, 957t Epigenetic modulation
characteristics, 1916t, 1932 in skin disorders, 954, 955t, 956t for acute myelogenous leukemia, 1403
functions, 1932, 1949, 1952t, 1968 Eosinophilic bronchitis, 954 for polycythemia vera, 1300
gene structure and variations, 1932 Eosinophilic fasciitis, 518, 960 Epigenetic regulation, 213
in inflammation, 2202 Eosinophilic granuloma. See Langerhans cell Epigenetics, 151, 165–170
protein C activation and, 1932, 1954 histiocytosis chromatin factors in. See Chromatin
in sepsis, 2202 Eosinophilic granulomatosis with definition and overview, 165
structure, 1932, 1951f, 1952t, 1972 polyangiitis (EGPA), 959–960, 2107 DNA methylation/demethylation, 168–170

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