Page 2505 - Williams Hematology ( PDFDrive )

2476 Index Index 2477

Pentraxin-3, 1013t, 1014 autoimmune diseases and, 600 PHD2, 510, 875
Peptide vaccines, for myeloid leukemias, 423 blood films, 594f PHDs (proline hydroxylases), 486, 486f
Peptidylprolyl isomerase (PIN1), 951 gastric disorders in, 600 PHEMX. See TSSC6
PER-ARNT-SIM (PAS)-domain, 486 in hypothyroidism, 559 Phenazopyridine, 5
Percutaneous coronary intervention (PCI), inherited predisposition to, 600 Phenformin, megaloblastic anemia and, 606t
2295 marrow films, 595f Phenobarbital
Percutaneous umbilical blood sampling, 854 stomach and intestine in, 583, 600–601, maternal ingestion of, effect on fetus and
Perforin, 1114, 1145, 1228, 1567 601f newborn, 112
Performance status, 3, 4t true juvenile, 607 megaloblastic anemia and, 606t
Periarterial lymphoid sheath (PALS), 88, 89f, Peroxidase, promonocytes and, 1046 Phenotype, 147
90f Peroxidase-negative neutrophil granules, Phenotypic mosaicism, in paroxysmal
Pericentric inversion, 175t 1009, 1012–1013t, 1013–1014. See nocturnal hemoglobinuria, 573,
Pericytes, 1008 also Neutrophils, granules 574–575f
Perifosine, for acute myelogenous leukemia, Peroxidase-positive neutrophil granules, Phenylbutazone, maternal ingestion of, effect
1403 1009. See also Neutrophils, granules on fetus and newborn, 112
Peripheral arterial disease (PAD), 2297 Peroxiredoxin 2, 699 Phenytoin
Peripheral blood progenitor cells (PBPCs), Peroxisome proliferator-activated receptor maternal ingestion of, effect on fetus and
355–356 (PPAR), 197, 452, 1873–1874 newborn, 109, 112, 112t
Peripheral membrane proteins. See Peroxisomes, platelet, 1840 megaloblastic anemia and, 606t
Membrane proteins, peripheral Peroxynitrite, 284t, 2203 Pheochromocytomas, 560, 879
Peripheral T-cell lymphoma (PTCL) Persistent lymphocytosis, 1204 PHF6, 227t, 233t, 1346t
chromosomal abnormalities, 185t Persistent polyclonal lymphocytosis of B Philadelphia (Ph) chromosome
classification, 1693, 1694t lymphocytes (PPBL), 1200–1202, in acute lymphoblastic leukemia, 183, 364,
diagnosis, 1693–1694 1201f 1517, 1521
epidemiology, 1693, 1694t Pertussis. See Bordetella pertussis infections in acute myelogenous leukemia, 1385,
laboratory features, 1498t, 1598, 1598f Pesticides, lymphoma and, 1571, 1572–1573 1407
prognosis, 1694, 1695t PETA-3. See CD151 characteristics, 1441, 1441f, 1448f
subtypes PET-CT. See FDG-PET in chronic myelogenous leukemia, 176,
adult T-cell leukemia/lymphoma. See Petechiae, 6, 8, 1987 178, 1278, 1438–1440, 1447, 1452
Adult T-cell leukemia/lymphoma Peyer patches, 94, 94f in clonal myeloid diseases, 1450
(ATL/ATLL) PF4. See CXCL4 (platelet factor 4) in eosinophilic chronic myelogenous
anaplastic large cell lymphoma. See PFK. See Phosphofructokinase (PFK) leukemia, 1445
Anaplastic large cell lymphoma PFKL, 695 masked, 1447
(ALCL) PFKM, 695 Philadelphia chromosome–like acute
angioimmunoblastic T-cell lymphoma, PGA (polyglandular autoimmune) syndrome, lymphoblastic leukemia, 177f, 186
1498t, 1598, 1697–1698 87 Philadelphia chromosome-negative chronic
enteropathy-associated T-cell PGK. See Phosphoglycerate kinase (PGK) myelogenous leukemia, 1450
lymphoma, 1699–1700 P-gp, 1404 Philadelphia chromosome-positive
extranodal NK/T-cell lymphoma, Phagocytes eosinophilic chronic myelogenous
nasal type, 1498t, 1500t, 1573, cell surface proteins, 1017 leukemia, 1445
1701–1702 killing and degradation of microorganisms Phlebotomy
hepatosplenic T-cell lymphoma, 185t, in, 284t for bleeding in chronic myeloproliferative
1498t, 1567, 1701 mononuclear. See Macrophages; neoplasms, 2081
peripheral T-cell lymphoma, not Monocytes for hemochromatosis, 644
otherwise specified, 1694t, 1695t, in newborn, 105–106 for polycythemia vera, 1298t, 1299–1300
1697 respiratory burst, 1068f for porphyria cutanea tarda, 908
subcutaneous panniculitis-like T-cell Phagocytosis PHMX. See TSSC6
lymphoma, 1498t, 1702 evasion of, 1064f Phorbol myristate acetate (PMA), 1011
treatment in inflammatory response, 279, 284 Phosphatases, 253
initial, 1694–1696, 1695t pathways, 1061–1062, 1061f, 1062f, 1063f Phosphatidylethanolamine, 1955
for relapsed or refractory disease, surface components for, 1008–1009 Phosphatidylinositol-4,5-bisphosphate, 1016
1696–1697, 1696t Pharmacologic chaperones, 1128 Phosphatidylinositol-4-monophosphate,
Peripheral vascular disease, 2240, 2316–2317 pH change sensing, for DNA sequencing, 1016
Pernicious anemia (PA), 600. See also 157–158, 157f Phosphatidylserine, 1060, 1061f
Cobalamin deficiency Ph chromosome. See Philadelphia (Ph) Phosphatidyl serine antibody assay, 2242
in adrenal insufficiency, 560 chromosome Phosphatidylserine exposure model, 498

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