Page 2503 - Williams Hematology ( PDFDrive )

2474 Index Index 2475

Oligoclonal immunoglobulins, 1725–1726 of the jaw, 1757 p27 kip1 , 218
Oligodendrocyte progenitor cells (OPCs), Osteopenia, 771 p38 kinases, 298, 301f
452 Osteopetrosis, 1091 p40 phox (NCF4), 1029
Omacetaxine, 1458, 1466 Osteopontin, 64, 1846t p47 phox (NCF1), 1028t, 1029
Omega-3-fatty acids Osteoporosis p53
for sickle cell disease, 777t acute lymphoblastic leukemia treatment apoptosis and, 208f, 209
for stroke prevention, 2297 and, 1520 cancer and, 132, 195, 210, 238
Omenn syndrome, 1166, 1219–1220 heparin-induced, 2277 in chronic myelogenous leukemia
Omeprazole, megaloblastic anemia and, 605, mast cell numbers and, 972 transformation, 1464
606t in mastocytosis, 977 functions, 195
Oncogenes, 219. See also Chromosomal in sickle cell disease, 771 vascular tone and, 2283
abnormalities; Gene mutations Osteoprotegerin (OPG), 249, 1713, 1737, p53
Oncostatin M, 248, 933t, 1978 1738f, 1739f in diffuse large B-cell lymphoma, 1626
One-compartment model, 430f Osteosclerosis, 1325, 1330 in mantle cell lymphoma, 1654
Onion extract, 2079 Osteosclerotic myeloma (POEMS syndrome), in myeloma, 1710
OPCs (oligodendrocyte progenitor cells), 452 9, 1733, 1746 p55, 663t, 667, 667f
Open canalicular system, 1835f, 1836 Ostwald viscosimeter, 506 p67 phox (NCF2), 1028t, 1029
OPG (osteoprotegerin), 249, 1713, 1737, Ovalocytes. See Elliptocytes (ovalocytes) p107, 217, 238
1738f, 1739f Ovary, primary lymphomas in, 1582 p130, 238
Opioids, for sickle cell disease pain, 767–768 Owren parahemophilia, 1925 P140K-MGMT, 442, 443f
Oprelvekin, 1358 Oxidant damage, hemolysis and, 809–810 p190, 1442
Oprozomib, for myeloma, 1753 2-Oxoglutarate (2OG, α-ketoglutarate), 169, p205 radixin, 1006
Opsonic receptors, 934t, 1054 193, 196 p210 BCR-ABL , 1440–1441, 1442–1443
Opsonins, 106, 284, 1017, 1054 Oxygen dissociation curve, 761 p230, 1442
Opsonization, 1160 Oxygen gas, hemolytic anemia and, 809–810 PA. See Pernicious anemia (PA)
ORAI1 (Orai1), 1221, 1836 Oxygen transport PACAP, 2061
Oral cavity, history of disorders of, 5 anemia and, 504–505, 504f, 505f Pacific Biosciences real-time sequencing,
Oral contraceptives hemoglobin and, 761 158–159, 158f
venous thromboembolism risk and, 2226t, hypervolemia and, 506, 510f Paclitaxel, 326, 1631, 2297
2227 in red cells in newborn, 104, 104f PAD (peripheral arterial disease), 2297
for von Willebrand disease, 2176 Oxymetholone, for anemia of primary PADGEM. See P-selectin
Oral hairy leukoplakia, 1266 myelofibrosis, 1328 PAF. See Platelet-activating factor (PAF)
Orbital adnexal lymphoma, 1571, 1579 Ozone, 809–810 Pagetoid reticulosis, 1683
Orbital compression syndrome, 772 PAI-1. See Plasminogen activator inhibitor
Organic acids, in erythrocytes, 471t P (PAI)-1
Organismal aging, 132 P1PK blood group/antigens, 2331t, 2334t, Pain
ORMDL3 (orosomucoid-like 3), 950 2337, 2339, 2340, 2344t abdominal, history of, 5
Ornithine decarboxylase (ODC), 200, 238 P2RY8, 1508 bone, history of, 6
Oropharynx, history of disorders of, 5 P2X , 1874, 2056–2057 chest, history of, 5
1
Orosomucoid-like 3 (ORMDL3), 950 P2Y , 1874–1875 shoulder, history of, 6
1
Oroya fever (Bartonella infection), 818, 997 P2Y , 1874–1875, 2056–2057 in sickle cell disease, 767–768
12
Orthochromic (orthochromatic) P4P (polyphosphate-4-phosphatase), 1817 in tongue, history of, 5
erythroblasts, 34, 463f, 465, 465f p14 ARF , 218, 238 Palbociclib, 215, 218
Orthochromic normoblast, 463f p15 (CDKN2B), 232t Palifermin, 368
Orthopedic surgery, 2371 p16 (CDKN2), 232t, 236t, 1654, 1734 Pallor
Oseltamivir, 386 p16 (INK4A/ARF), 230t eyes, 8
Osteoblasts, marrow, 35, 60 p16 INK4A , 214, 238 history of, 6
Osteoclasts p16 INK4A /cyclin D /cdk4/RB/E24 cascade, 215, mouth, 8
1
deficiency, 1091 217 skin, 7
development, 1077, 1077f, 1078 p16 INK4A -RB pathway, 214, 225 Palpitations, history of, 5
markers, 1080t p16 INK4B , 218 PALS (periarterial lymphoid sheath), 88, 89f,
marrow, 35, 60–61 p16 INK4C , 218 90f
Osteogenesis imperfecta, 2061 p16 INK4D , 218 Pamidronate, 1756
Osteomyelitis, 771, 1513 p21 , 217–218, 225 Pancreas, 452
cip1
Osteonecrosis p22 phox (CYBA), 1013t, 1027, 1028t, 1029 Pancreatic disease
in Gaucher disease, 1125f P24. See CD9 cobalamin deficiency and, 602

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