Page 2533 - Williams Hematology ( PDFDrive )

2504 Index Index 2505

Waldenström macroglobulinemia (WM) Weight loss, history of, 3 Xg blood group/antigens, 104, 2331t, 2337,
(Cont.): Weisses Blut, 1438 2345t
platelet dysfunction in, 2082 WGBS (whole-genome bisulfite sequencing), XIAP, 204f, 207, 210, 218
treatment, 1792–1797 162 ξ-globin chain, 728
alkylating agents, 1793 WHIM syndrome, 994, 1226, 1787 X inactivation, 150, 150f
combination therapies, 1794–1795 White blood cell count (WBC) XIST, 150
everolimus, 1795–1796 fetal, 102 XK protein, 681. See also McLeod phenotype
hematopoietic cell transplantation, 1796 newborn, 105, 105t X-linked adrenoleukodystrophy, 439
ibrutinib, 1795 in pregnancy, 119 X-linked agammaglobulinemia (XLA), 993,
initiation, 1792–1793 reference ranges, 18t 1212–1213, 1214t
maintenance therapy, 1796 White pulp, of spleen, 88, 89f, 90f X-linked anhydrotic ectodermal dysplasia
nucleoside analogues, 1793–1794 White thrombi, 2291 with immunodeficiency caused by
proteasome inhibitors, 1794 Whole-genome bisulfite sequencing (WGBS), NEMO mutations, 1215
response criteria, 1796–1797, 1796t 162 X-linked chronic granulomatous disease,
rituximab, 1794 WHSC1 (MMSET), 236t, 1735 1029, 1030–1031, 1031t
Waldeyer ring, 94 Wilms tumor, erythrocytosis and, 879 X-linked hyperimmunoglobulin
Wandering spleen, 865–866 Wilms tumor antigen-1 (WT-1), 414 M syndromes. See
Warburg effect, 504 Wilson disease, 810f, 811 Hyperimmunoglobulin M
Warfarin, 393–397 WIP (WASp-interacting protein) deficiency, syndromes
administration and monitoring, 394–395 1225 X-linked inheritance, 149–151
adverse effects, 396, 2100, 2100f, 2223, Wiskott-Aldrich syndrome (WAS), X-linked lymphoproliferative disease,
2277 1224–1225 1228–1229, 1266, 1575t
for antiphospholipid syndrome, 2244 clinical and laboratory features, 1215t, X-linked protoporphyria (XLP), 889, 890t,
complications, 395–396, 396t 1225, 2059 891t, 896
contraindication during pregnancy, 580 definition, 1224–1225 X-linked severe combined immune
drug interactions, 394t gene therapy, 439 deficiency, 437, 439, 1217.
in heparin-induced thrombocytopenia, hyposplenism and, 868 See also Severe combined
2031–2032 lymphocytopenia in, 1204 immunodeficiency (SCID)
maternal ingestion of lymphomas and, 1575t X-linked sideroblastic anemia (XLSA), 894,
effect on fetus and newborn, 112, 112t macrophages in, 1059 916–917, 920
neonatal hemorrhage and, 109 neutropenia in, 993 X-linked sideroblastic anemia with ataxia
for myocardial infarction, 2296 pathogenesis, 2059 (XLSA/A), 918
pharmacology, 394 treatment, 2059 X-linked thrombocytopenia, 1224–1225,
reversal, 396–397, 396t Wiskott-Aldrich syndrome protein 2059
for venous thromboembolism, 2274 (WASp/WASP), 60, 439, 1063f, XPO1, 231t, 1529
Warm-antibody autoimmune hemolytic 1224, 1841, 2059–2060 X-ray repair complementing defective
anemia. See Autoimmune WM. See Waldenström macroglobulinemia repair in Chinese hamster cells 4
hemolytic anemia, warm-antibody (WM) (XRCC4), 1167
WAS. See Wiskott-Aldrich syndrome (WAS) Wnt pathway, 232t, 237
WASP (Wiskott-Aldrich syndrome protein), Wnt proteins, 266 Y
2059–2060 Women. See also Pregnancy Yellow marrow, 28
WASp-interacting protein (WIP) deficiency, iron deficiency in, 630 Yersinia enterocolitica, 742
1225 menorrhagia in, 5–6, 1987, 2007, 2135, 90 Y-ibritumomab tiuxetan, 346
Wasp stings, 809 2139 adverse effects, 343t
WASp/WASP (Wiskott-Aldrich syndrome rare bleeding disorders in, 2135 for diffuse large B-cell lymphoma, 1632
protein), 60, 439, 1063f, 1224, Woringer-Kolopp disease, 1683 for follicular lymphoma, 1647
1841 Work performance, iron deficiency and, in hematopoietic cell transplantation,
Water 632 360
in erythrocytes, 469t WT1, 227t, 863, 1378t, 1379, 1465 for MALT lymphoma, 1666
in lymphocytes, 1143 WT1 vaccine, 423, 1404 for mantle cell lymphoma, 1657t
Waterhouse-Friderichsen syndrome, 2207 WT syndrome, 530t mechanism of action, 343t
WBC. See White blood cell count (WBC) Yolk sac, hematopoiesis in, 54, 99–100, 100f,
Weakness, history of, 4 X 257–258
Wee1, 219 X-chromosome–based polymorphism assays, Yt blood group/antigens, 2331t, 2337,
Wegener granulomatosis, 1013, 2107, 2107f 883 2345t
Weibel-Palade bodies, 281, 2166 Xerocytosis, hereditary, 682t, 683 90 Yttrium, 360

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