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276 Part IV: Molecular and Cellular Hematology Chapter 18: Hematopoietic Stem Cells, Progenitors, and Cytokines 277

246. Legras S, Levesque JP, Charrad R, et al: CD44-mediated adhesiveness of human 277. Nerlov C, Querfurth E, Kulessa H, et al: GATA-1 interacts with the myeloid PU.1 tran-
hematopoietic progenitors to hyaluronan is modulated by cytokines. Blood 89:1905, scription factor and represses PU.1-dependent transcription. Blood 95:2543, 2000.
1997. 278. Zhang P, Zhang X, Iwama A, et al: PU.1 inhibits GATA-1 function and erythroid differ-
247. Bendall LJ, James A, Zannettino A, et al: A novel CD44 antibody identifies an epitope entiation by blocking GATA-1 DNA binding. Blood 96:2641, 2000.
that is aberrantly expressed on acute lymphoblastic leukaemia cells. Immunol Cell Biol 279. Kondo M, Scherer DC, Miyamoto T, et al: Cell-fate conversion of lymphoid-committed
81:311, 2003. progenitors by instructive actions of cytokines. Nature 407:383, 2000.
248. Bendall LJ, Kirkness J, Hutchinson A, et al: Antibodies to CD44 enhance adhesion of 280. Metcalf D: Lineage commitment in the progeny of murine hematopoietic preprogenitor
normal CD34+ cells and acute myeloblastic but not lymphoblastic leukaemia cells to cells: Influence of thrombopoietin and interleukin 5. Proc Natl Acad Sci U S A 95:6408,
bone marrow stroma. Br J Haematol 98:828, 1997. 1998.
249. Pilarski LM, Pruski E, Wizniak J, et al: Potential role for hyaluronan and the hyaluronan 281. Barroga C, Pham H, Kaushansky K: Thrombopoietin regulates c-myb expression by
receptor RHAMM in mobilization and trafficking of hematopoietic progenitor cells. modulating microRNA (miR)150 expression. Exp Hematol 36:1585, 2008.
Blood 93:2918, 1999. 282. de Laval B, Pawlikowska P, Petit-Cocault L, et al: Thrombopoietin-increased DNA-P-
250. Nilsson SK, Haylock DN, Johnston HM, et al: Hyaluronan is synthesized by primitive K-dependent DNA repair limits hematopoietic stem and progenitor cell mutagenesis in
hemopoietic cells, participates in their lodgment at the endosteum following trans- response to DNA damage. Cell Stem Cell 12:37, 2013.
plantation, and is involved in the regulation of their proliferation and differentiation in 283. Zimdahl B, Ito T, Blevins A, et al: Lis1 regulates asymmetric division in hematopoietic
vitro. Blood 101:856, 2003. stem cells and in leukemia. Nat Genet 46:245, 2014.
251. Gupta P, Oegema TR Jr, Brazil JJ, et al: Structurally specific heparan sulfates support 284. Thorsteinsdottir U, Sauvageau G, Humphries RK: Enhanced in vivo regenerative poten-
primitive human hematopoiesis by formation of a multimolecular stem cell niche. tial of HOXB4-transduced hematopoietic stem cells with regulation of their pool size.
Blood 92:4641, 1998. Blood 94:2605, 1999.
252. Klein G, Beck S, Muller CA: Tenascin is a cytoadhesive extracellular matrix component 285. Iscove NN, Nawa K: Hematopoietic stem cells expand during serial transplantation in
of the human hematopoietic microenvironment. J Cell Biol 123:1027, 1993. vivo without apparent exhaustion. Curr Biol 7:805, 1997.
253. Seiffert M, Beck SC, Schermutzki F, et al: Mitogenic and adhesive effects of tenascin-C 286. Wilpshaar J, Bhatia M, Kanhai HH, et al: Engraftment potential of human fetal hemato-
on human hematopoietic cells are mediated by various functional domains. Matrix Biol poietic cells in NOD/SCID mice is not restricted to mitotically quiescent cells. Blood
17:47, 1998. 100:120, 2002.
254. Ohta M, Sakai T, Saga Y, et al: Suppression of hematopoietic activity in tenascin-C- 287. Czechowicz A, Kraft D, Weissman IL, Bhattacharya D: Efficient transplantation via
deficient mice. Blood 91:4074, 1998. antibody-based clearance of hematopoietic stem cell niches. Science 318:1296, 2007.
255. Siler U, Seiffert M, Puch S, et al: Characterization and functional analysis of laminin 288. Fuchs E, Tumbar T, Guasch G: Socializing with the neighbors: Stem cells and their
isoforms in human bone marrow. Blood 96:4194, 2000. niche. Cell 116:769, 2004.
256. Gu Y, Sorokin L, Durbeej M, et al: Characterization of bone marrow laminins and iden- 289. Mezey E, Chandross KJ, Harta G, et al: Turning blood into brain: Cells bearing neu-
tification of alpha5-containing laminins as adhesive proteins for multipotent hemato- ronal antigens generated in vivo from bone marrow. Science 290:1779, 2000.
poietic FDCP-Mix cells. Blood 93:2533, 1999. 290. Brazelton TR, Rossi FM, Keshet GI, et al: From marrow to brain: Expression of neu-
257. Siler U, Rousselle P, Muller CA, et al: Laminin gamma2 chain as a stromal cell marker ronal phenotypes in adult mice. Science 290:1775, 2000.
of the human bone marrow microenvironment. Br J Haematol 119:212, 2002. 291. Lagasse E, Connors H, Al-Dhalimy M, et al: Purified hematopoietic stem cells can dif-
258. Landowski TH, Dratz EA, Starkey JR: Studies of the structure of the metastasis- ferentiate into hepatocytes in vivo. Nat Med 6:1229, 2000.
associated 67 kDa laminin binding protein: Fatty acid acylation and evidence support- 292. Alison MR, Poulsom R, Jeffery R, et al: Hepatocytes from non-hepatic adult stem cells.
ing dimerization of the 32 kDa gene product to form the mature protein. Biochemistry Nature 406:257, 2000.
34:11276, 1995. 293. Ferrari G, Cusella-De Angelis G, Coletta M, et al: Muscle regeneration by bone mar-
259. Ardini E, Tagliabue E, Magnifico A, et al: Co-regulation and physical association of row-derived myogenic progenitors. Science 279:1528, 1998.
the 67-kDa monomeric laminin receptor and the alpha6beta4 integrin. J Biol Chem 294. Orlic D, Kajstura J, Chimenti S, et al: Bone marrow cells regenerate infarcted myocar-
272:2342, 1997. dium. Nature 410:701, 2001.
260. Gu YC, Kortesmaa J, Tryggvason K, et al: Laminin isoform-specific promotion of adhe- 295. Jiang Y, Jahagirdar BN, Reinhardt RL, et al: Pluripotency of mesenchymal stem cells
sion and migration of human bone marrow progenitor cells. Blood 101:877, 2003. derived from adult marrow. Nature 418:41, 2002.
261. Chen J, Carcamo JM, Borquez-Ojeda O, et al: The laminin receptor modulates granulo- 296. Ying QL, Nichols J, Evans EP, et al: Changing potency by spontaneous fusion. Nature
cyte-macrophage colony-stimulating factor receptor complex formation and modulates 416:545, 2002.
its signaling. Proc Natl Acad Sci U S A 100:14000, 2003. 297. Terada N, Hamazaki T, Oka M, et al: Bone marrow cells adopt the phenotype of other
262. Klein G, Muller CA, Tillet E, et al: Collagen type VI in the human bone marrow micro- cells by spontaneous cell fusion. Nature 416:542, 2002.
environment: A strong cytoadhesive component. Blood 86:1740, 1995. 298. Galy A, Travis M, Cen D, et al: Human T, B, natural killer, and dendritic cells arise from
263. Ergen AV, Boles NC, Goodell MA: Rantes/Ccl5 influences hematopoietic stem cell sub- a common bone marrow progenitor cell subset. Immunity 3:459, 1995.
types and causes myeloid skewing. Blood 119:2500, 2012. 299. von Freeden-Jeffry U, Vieira P, Lucian LA, et al: Lymphopenia in interleukin (IL)-7
264. Metcalf D: Lineage commitment and maturation in hematopoietic cells: The case for gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 181:1519,
extrinsic regulation. Blood 92:345; discussion 352, 1998. 1995.
265. Enver T, Heyworth CM, Dexter TM: Do stem cells play dice? Blood 92:348; discussion 300. Terskikh AV, Miyamoto T, Chang C, et al: Gene expression analysis of purified hemato-
352, 1998. poietic stem cells and committed progenitors. Blood 102:94, 2003.
266. Souabni A, Cobaleda C, Schebesta M, et al: Pax5 promotes B lymphopoiesis and blocks 301. Ikawa T, Kawamoto H, Fujimoto S, et al: Commitment of common T/natural killer
T cell development by repressing Notch1. Immunity 17:781, 2002. (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus
267. Georgopoulos K, Moore DD, Derfler B: Ikaros, an early lymphoid-specific transcription revealed by a single progenitor assay. J Exp Med 190:1617, 1999.
factor and a putative mediator for T cell commitment. Science 258:808, 1992. 302. Massari ME, Murre C: Helix-loop-helix proteins: Regulators of transcription in eucary-
268. Hromas R, Orazi A, Neiman RS, et al: Hematopoietic lineage- and stage-restricted otic organisms. Mol Cell Biol 20:429, 2000.
expression of the ETS oncogene family member PU.1. Blood 82:2998, 1993. 303. Sawada S, Littman DR: A heterodimer of HEB and an E12-related protein interacts with
269. Hohaus S, Petrovick MS, Voso MT, et al: PU.1 (Spi-1) and C/EBP alpha regulate expres- the CD4 enhancer and regulates its activity in T-cell lines. Mol Cell Biol 13:5620, 1993.
sion of the granulocyte-macrophage colony-stimulating factor receptor alpha gene. Mol 304. Takeuchi A, Yamasaki S, Takase K, et al: E2A and HEB activate the pre-TCR alpha
Cell Biol 15:5830, 1995. promoter during immature T cell development. J Immunol 167:2157, 2001.
270. Martin DI, Zon LI, Mutter G, et al: Expression of an erythroid transcription factor in 305. Bain G, Romanow WJ, Albers K, et al: Positive and negative regulation of V(D)J recom-
megakaryocytic and mast cell lineages. Nature 344:444, 1990. bination by the E2A proteins. J Exp Med 189:289, 1999.
271. Hart A, Melet F, Grossfeld P, et al: Fli-1 is required for murine vascular and megakary- 306. Norton JD: ID helix-loop-helix proteins in cell growth, differentiation and tumorigen-
ocytic development and is hemizygously deleted in patients with thrombocytopenia. esis. J Cell Sci 113 Pt 22:3897, 2000.
Immunity 13:167, 2000. 307. Yokota Y, Mansouri A, Mori S, et al: Development of peripheral lymphoid organs and
272. Gombart AF, Kwok SH, Anderson KL, et al: Regulation of neutrophil and eosinophil natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 397:702, 1999.
secondary granule gene expression by transcription factors C/EBP epsilon and PU.1. 308. Heemskerk MH, Blom B, Nolan G, et al: Inhibition of T cell and promotion of natural
Blood 101:3265, 2003. killer cell development by the dominant negative helix loop helix factor Id3. J Exp Med
273. Enver T: B-cell commitment: Pax5 is the deciding factor. Curr Biol 9:R933, 1999. 186:1597, 1997.
274. Zhang DE, Zhang P, Wang ND, et al: Absence of granulocyte colony-stimulating factor 309. Pui JC, Allman D, Xu L, et al: Notch1 expression in early lymphopoiesis influences B
signaling and neutrophil development in CCAAT enhancer binding protein alpha-de- versus T lineage determination. Immunity 11:299, 1999.
ficient mice. Proc Natl Acad Sci U S A 94:569, 1997. 310. Allman D, Karnell FG, Punt JA, et al: Separation of Notch1 promoted lineage commit-
275. Cammenga J, Mulloy JC, Berguido FJ, et al: Induction of C/EBPalpha activity alters ment and expansion/transformation in developing T cells. J Exp Med 194:99, 2001.
gene expression and differentiation of human CD34+ cells. Blood 101:2206, 2003. 311. Denis KA, Witte ON: In vitro development of B lymphocytes from long-term cultured
276. Fairbairn LJ, Cowling GJ, Reipert BM, et al: Suppression of apoptosis allows differenti- precursor cells. Proc Natl Acad Sci U S A 83:441, 1986.
ation and development of a multipotent hemopoietic cell line in the absence of added 312. Takatsu K: Cytokines involved in B-cell differentiation and their sites of action. Proc Soc
growth factors. Cell 74:823, 1993. Exp Biol Med 215:121, 1997.

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