Page 1057 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPter 75 Immunological Diseases of the Gastrointestinal Tract 1019.e1

MUL t IPL e -CHOIC e QU est IO ns

1. A 73-year-old Caucasian female who is undergoing workup and reports a history of irritable bowel syndrome (IBD). She
for chronic diarrhea and weight loss has been incidentally says that her primary physician performed a “celiac test but
found to have a gastrin level of 2500 pg/mL and have serum it was negative.” Your first choice of tests is:
immunoglobulin G (IgG) antibody positive for Helicobacter A. Esophagogastroduodenoscopy with biopsies of the duo-
pylori. There is no history of peptic ulcer disease, pyrosis, or denum and duodenal bulb
kidney stones, and yet she has been referred for evaluation B. Genetic human leukocyte antigen (HLA) testing for DQ2
for gastrinoma. The first test you order is: and DQ8 risk alleles
A. Esophagogastroduodenoscopy with biopsy C. Repeat testing for serum IgA antibodies to tissue trans-
B. Abdominal computed tomography (CT) glutaminase, including total serum IgA level
C. Serologic testing for celiac disease D. Monitor anti–tissue transglutaminase levels while the patient
D. Secretin stimulation test is on a gluten-free diet
E. Fecal testing for H. pylori antigen
3. Which of the following is characteristic of ulcerative
2. A 22-year-old Caucasian female is referred for chronic colitis?
abdominal pain and bloating. She reports that a cousin has A. Presence of antiflagellin antibodies
celiac disease, and she says that “every time that I eat bread, B. Inflammation of the full thickness of the bowel wall
I feel bad and get diarrhea.” She has maintained her weight C. Tobacco use increases the frequency
and has no other specific symptoms. She is on no medications D. Surgery can be curative