Page 1205 - Hall et al (2015) Principles of Critical Care-McGraw-Hill
P. 1205
2 References
medical intensive care unit patients. Crit Care Med. December mechanically ventilated patients and healthy subjects. Am J
2007;35(12):2721-2724; quiz 2725. Respir Crit Care Med. March 1, 2003;167(5):708-715.
27. Spronk PE, Riekerk B, Hofhuis J, Rommes JH. Occurrence of 44. Hardin KA. Sleep in the ICU: potential mechanisms and clinical
delirium is severely underestimated in the ICU during daily implications. Chest. July 2009;136(1):284-294.
care. Intensive Care Med. July 2009;35(7):1276-1280. 45. Bourne RS, Mills GH. Sleep disruption in critically ill
28. van Eijk MM, van Marum RJ, Klijn IA, de Wit N, Kesecioglu J, patients–pharmacological considerations. Anaesthesia. April
Slooter AJ. Comparison of delirium assessment tools in a mixed 2004;59(4):374-384.
intensive care unit. Crit Care Med. June 2009;37(6):1881-1885. 46. Kress JP, Pohlman AS, O’Connor MF, Hall JB. Daily interruption
29. Epstein SK, Ciubotaru RL, Wong JB. Effect of failed extuba- of sedative infusions in critically ill patients undergoing mechan-
tion on the outcome of mechanical ventilation. Chest. July ical ventilation. N Engl J Med. May 18, 2000;342(20):1471-1477.
1997;112(1):186-192. 47. Agarwal V, O'Neill PJ, Cotton BA, et al. Prevalence and risk
30. Hopkins RO, Miller RR III, Key CW, Kuttler K, Rodriquez L, factors for development of delirium in burn intensive care
Thomsen GE. Delirium reduced ambulation in respiratory fail- unit patients. J Burn Care Res. September-October 2010;31(5):
ure patients who underwent early activity. Am J Respir Crit Care 706-715.
Med. 2009;179:A5475. 48. Strom T, Martinussen T, Toft P. A protocol of no sedation for
31. Kollef MH, Levy NT, Ahrens TS, Schaiff R, Prentice D, critically ill patients receiving mechanical ventilation: a ran-
Sherman G. The use of continuous IV sedation is associated domised trial. Lancet. February 6, 2010;375(9713):475-480.
with prolongation of mechanical ventilation. Chest. August 49. Flacker JM, Lipsitz LA. Neural mechanisms of delirium: current
1998;114(2):541-548. hypotheses and evolving concepts. J Gerontol A Biol Sci Med Sci.
32. Ely EW, Gautam S, Margolin R, et al. The impact of delirium in June 1999;54(6):B239-B246.
the intensive care unit on hospital length of stay. Intensive Care 50. Hshieh TT, Fong TG, Marcantonio ER, Inouye SK. Cholinergic
Med. December 2001;27(12):1892-1900. deficiency hypothesis in delirium: a synthesis of current evi-
33. Inouye SK, Charpentier PA. Precipitating factors for delirium dence. J Gerontol A Biol Sci Med Sci. July 2008;63(7):764-772.
in hospitalized elderly persons. Predictive model and inter- 51. Gunther ML, Morandi A, Ely EW. Pathophysiology of delirium
relationship with baseline vulnerability. JAMA. March 20, in the intensive care unit. Crit Care Clin. January 2008;24(1):
1996;275(11):852-857. 45-65, viii.
34. Ely EW, Girard TD, Shintani AK, et al. Apolipoprotein E4 poly- 52. Maldonado JR. Pathoetiological model of delirium: a compre-
morphism as a genetic predisposition to delirium in critically ill hensive understanding of the neurobiology of delirium and an
patients. Crit Care Med. January 2007;35(1):112-117. evidence-based approach to prevention and treatment. Crit
35. Aldemir M, Ozen S, Kara IH, Sir A, Bac B. Predisposing Care Clin. October 2008;24(4):789-856, ix.
factors for delirium in the surgical intensive care unit. Crit Care. 53. Trzepacz PT. Update on the neuropathogenesis of delirium.
October 2001;5(5):265-270. Dement Geriatr Cogn Disord. September-October 1999;
36. Ouimet S, Kavanagh BP, Gottfried SB, Skrobik Y. Incidence, risk 10(5):330-334.
factors and consequences of ICU delirium. Intensive Care Med. 54. Inouye SK. Delirium in older persons. N Engl J Med. March 16,
January 2007;33(1):66-73. 2006;354(11):1157-1165.
37. Van Rompaey B, Elseviers MM, Schuurmans MJ, Shortridge- 55. Flacker JM, Lipsitz LA. Large neutral amino acid changes and
Baggett LM, Truijen S, Bossaert L. Risk factors for delirium in delirium in febrile elderly medical patients. J Gerontol A Biol Sci
intensive care patients: a prospective cohort study. Crit Care. Med Sci. May 2000;55(5):B249-252; discussion B253-244.
2009;13(3):R77. 56. van der Mast RC, Fekkes D. Serotonin and amino acids: part-
38. Pandharipande P, Ely EW. Sedative and analgesic medications: ners in delirium pathophysiology? Semin Clin Neuropsychiatry.
risk factors for delirium and sleep disturbances in the critically April 2000;5(2):125-131.
ill. Crit Care Clin. April 2006;22(2):313-327, vii. 57. Robinson TN, Raeburn CD, Angles EM, Moss M. Low trypto-
39. Pisani MA, Murphy TE, Araujo KL, Slattum P, Van Ness PH, phan levels are associated with postoperative delirium in the
Inouye SK. Benzodiazepine and opioid use and the duration of elderly. Am J Surg. November 2008;196(5):670-674.
intensive care unit delirium in an older population. Crit Care 58. Pandharipande PP, Morandi A, Adams JR, et al. Plasma tryp-
Med. January 2009;37(1):177-183. tophan and tyrosine levels are independent risk factors for
40. Weinhouse GL, Schwab RJ, Watson PL, et al. Bench-to-bedside delirium in critically ill patients. Intensive Care Med. November
review: delirium in ICU patients—importance of sleep depriva- 2009;35(11):1886-1892.
tion. Crit Care. 2009;13(6):234. 59. Cerejeira J, Firmino H, Vaz-Serra A, Mukaetova-Ladinska
41. Figueroa-Ramos MI, Arroyo-Novoa CM, Lee KA, Padilla G, EB. The neuroinflammatory hypothesis of delirium. Acta
Puntillo KA. Sleep and delirium in ICU patients: a review Neuropathol. June 2010;119(6):737-754.
of mechanisms and manifestations. Intensive Care Med. May 60. van Gool WA, van de Beek D, Eikelenboom P. Systemic infec-
2009;35(5):781-795. tion and delirium: when cytokines and acetylcholine collide.
42. Cooper AB, Thornley KS, Young GB, Slutsky AS, Stewart TE, Lancet. February 27, 2010;375(9716):773-775.
Hanly PJ. Sleep in critically ill patients requiring mechanical 61. Maclullich AM, Ferguson KJ, Miller T, de Rooij SE, Cunningham
ventilation. Chest. March 2000;117(3):809-818. C. Unravelling the pathophysiology of delirium: a focus on
43. Gabor JY, Cooper AB, Crombach SA, et al. Contribution of the role of aberrant stress responses. J Psychosom Res. Sep
the intensive care unit environment to sleep disruption in 2008;65(3):229-238.
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