Page 161 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

TABLE 7.2 Red Blood Cell Morphology and Related Conditions (continued)

Associated Clinical Associated Clinical

RBC Morphology Conditions RBC Morphology Conditions

Crenated RBCs (echinocytes) Diseases—none Transiently accompanying a

hemolytic anemia

Result from osmotic imbalance

Elliptocytes Anemias associated with Target cells (codocytes) Hemoglobinopathies: Hb C

malignancy disease, S-C, S-S, sickle cell
thalassemia, thalassemia

Hb C disease

Hemolytic anemias Hemolytic anemias

(occasionally)

Hereditary elliptocytosis Hepatic disease with or without
jaundice

Iron de ciency anemia

Pernicious anemia Iron de ciency anemia

Sickle cell trait Postsplenectomy

Thalassemia Artifact

Keratocytes DIC Teardrops (dacryocytes) Homozygous beta-thalassemia

Myeloproliferative syndromes

Pernicious anemia

Severe anemias

Knizocytes Hemolytic anemia, including

hereditary spherocytosis

Leptocytes Hepatic disorders Alterations in color

Iron de ciency anemia Hypochromia Iron de ciency anemia

Thalassemia Polychromatophilia Rapid blood regeneration

Poikilocytosis Hemolytic anemias

Myelo brosis

Pernicious anemia

Thalassemia

RBC, red blood cell; G6PD, glucose-6-phosphate dehydrogenase; DIC, diffuse intravascular coagulation; Hb, hemoglobin.

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