Page 229 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 10 ■ Basic Laboratory Assessment of Erythrocytes, Leukocytes, and Platelets 213

TABLE 10.2 Values in the Measurement of Erythrocytes

Normal Adult Reference Values

Men Women

Conventional Units SI Conventional Units SI

Hematocrit

Packed cell volume 41.5–50.4% 0.415–0.504 L/L 36%–45% 0.36–0.45 L/L

12
12
6
6
Erythrocyte count 4.5–5.9 × 10 /µL 4.5–5.9 × 10 /L 4.5–5.1 × 10 /µL 4.5–5.1 × 10 /L
Hemoglobin

Concentration 14.0–18.0 g/dL 145–180 g/L 12.0–16.0 g/dL 120–160 g/L

Normal MCV 80–96 80–96 fL 80–96 80–96 fL

Normal MCH 27.5–33.2 27.5–33.2 pg 27.5–33.2 27.5–33.2 pg

Normal MCHC 33.4%–35.6% 32–36 g/dL 33.4%–35.6% 32–36 g/dL

Representative Average Pediatric Values

At birth (cord blood)

Packed cell volume 51%

Erythrocyte count 4.7 × 10 /L
12

Hemoglobin concentration 16.5 g/dL

MCV 108 fL

MCH 34 pg

At 6–12 years of age

Packed cell volume 40%

Erythrocyte count 4.6 × 10 /L
12

Hemoglobin concentration 13.5 g/dL

MCV 86 fL

MCH 29 pg

SI, Systeme International d’Unites.

Source: Perkins SL. Normal blood and bone marrow values in humans. In: Greer JP, et al. (eds.). Wintrobes’ Clinical Hematology, 11th ed, Philadelphia, PA:

Lippincott Williams & Wilkins, 2004:2607; Handin RI, Lux SE, Stossel TP. Blood, 2nd ed, Philadelphia, PA: Lippincott Williams & Wilkins, 2003; Appendix 25, Red
Blood Cell Values at Various Ages, p. 2216.

One femtoliter (fL) = 10 L = 1 cubic micrometer; One picogram (pg) = 10 g = 1 micromicrogram.
15
12

Mean Corpuscular Hem oglobin Clinical Conditions:

T MCH x ( ) m - I m m m ,

. I m m , m m

m z . T m , MCH .
Sources o Error:

H m ( × / L ) MCH m m m -
MCH = = m m
(
E × / L ) m m m . C m-

m m m -
Example: I ’ m / L m MCH .

× /L, MCH q

Mean Corpuscular Hem oglobin Concentration
/ L
MCH = = × - = T MCHC x m -
× / L
m m . I

b O m ( ) = − = m m m (µµ ) m

R ( ) MCH . . m . T m