Page 332 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

316 PART 4 ■ Erythrocyte Disorders

Epidemiology T m z k . T

x , m -
SCD m mm A - m m , m -

, M , C , k .

S C Am , A , E I - B m -

. T k carrier m m , m

P. alciparum m , k x m

z . T m m f

m . W k m

m m. m , m k

H SC m A m . T

Am , SC β m (S β m ) k

, A Am . A , x . T k x m k m

m mm U S . x . T

SCD, m z m SCD, m mm .

m m . M W k x , -

, Am SCD. m . R k k

T x SCD m RBC m m m . T

. T m - m , m . I ,

SCD m m , .

A Am

. F H SC , m Vasoocclusion

m m . T k -

m m vasoocclusion (F . .

Pathophysiology . ). S k -
m m -
Sickling m .

W H S x , m m z T m m -

k . S q m k ,

x ’ k . T - .

m m SCD m m

m , x z m Clinical Signs and Symptoms

m . I z

m H SS m , m A

m m m z m. m k . A m

P m z H S , k k

x m x . T , m m m -

. S k m x , H, . O

, - , -

m , , H C, H O–

A . S k H A, H F ( %), H J,

α m .

W k , q

m m (MCHC)

m m x

. D x m S x m -

A x m S.

R , m

SCD . I

m z x m S

m m m -

m . I

x , m

.

T m m m FIGURE 17.3 V k . (F m B k

m m m AP, P. Practical Cardiovascular Pathology, P , PA:

m x . L W m & W k , .)