Page 380 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )
P. 380
364 PART 5 ■ Nonmalignant Leukocyte Disorders
HIV
HIV virion (virus particle)
Lifecycle
HIV binds to the T-cell.
Viral RNA is released into
the host cell.
Reverse transcriptase
converts viral RNA into
viral DNA.
Viral DNA enters the T-
cell’s nucleus and inserts
Viral RNA itself into the T-cell’s DNA.
Reverse The T-cell begins to make
transcriptase copies of the HIV
components.
Protease (an enzyme)
helps create new virus
particles.
The new HIV virion (virus
particle) is released from
the T-cell.
Viral DNA
T-cell
Viral RNA
New HIV virion
(virus particle)
HIV proteins
FIGURE 19.6 HIV .
