Page 502 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

486 PART 6 ■ Neoplastic Disorders

CASE STUDIES (continued)
CASE STUDIES (continued)

Pl telets 10 × 10 /L
9
MCV 96 L

Te peripher l bloo s e r exhibite crocytic, hypo-

chro ic re bloo cells. A ew hyposeg ente neutrophils

were observe .

■ Follow-Up Laboratory Data
Reticulocyte count 0.3%

Bone rrow ex in tion reve le hypercellul r rrow

with yspl si o the he topoietic cells. T e Prussi n blue

st in w s positive or iron.

(Reprinte ro An erson SC. Anderson’s, Atlas o Hematology,
■ Critical Thinking Group Discussion Questions

1. Wh t is the c use o his elev te MCV? 2n e , Phil elphi , PA: Wolters Kluwer He lth/Lippincott
Willi s & Wilkins, 2003. Copyright 2003, with per ission.)

2. Wh t is the signif c nce o the hypercellul r bone rrow?
NOTE: This is a good time to write out the answers to the

Critical Thinking Group Discussion Questions.
3. Wh t coul be the potenti l c use o this p tient’s ne i ?

REVIEW QUESTIONS

*Indicates ML (optional) and MLS advanced content. 5. T e ost requent chro oso l bnor lities in chil-

ren with MDSs inclu e ll o the ollowing except

1. P tients with so e type o MDS re t incre se risk o A. triso y 8

eveloping B. onoso y 7

A. cute ly phobl stic leuke i C. eletion o long r o chro oso e 20

B. AML D. ll o the bove

C. chronic ly phocytic leuke i

D. chronic yelogenous leuke i 6. Te inci ence o chro oso l bnor lity in ults

with MDSs is

2. Which o the ollowing gents h s not been supporte A. 5% to 15%

by scientif c rese rch s being ssoci te with the evel- B. 15% to 25%

op ent o secon ry MDSs? C. 25% to 60%

A. Alkyl ting gents D. 40% to 90%

B. Org nic solvents

C. Insectici es 7. Te k ryotype ssoci te with high prob bility o

D. Both B n C tr ns or ing to AML is

A. onoso y 5

3. An incre se inci ence o MDSs is seen in B. onoso y 7

A. les younger th n 55 ye rs o ge C. triso y 11

B. e les younger th n 55 ye rs o ge D. both A n B

C. les ol er th n 55 ye rs o ge

D. e les ol er th n 55 ye rs o ge 8. P tients with MDSs co only su er ro

initi lly.

4. Te ost requently involve chro oso es in ults A. r sh

with MDSs re B. ne i

A. 1, 5, n 7 C. visu l isturb nces

B. 3, 5, n 8 D. vertigo

C. 5, 7, n 8

D. 8, 12, n 13