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CHAPTER 24  ■  Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms                                                    487







                                 REVIEW QUESTIONS (continued)





                        *9.  An   ppropri  te   escription o  re r  ctory   ne  i   (RA) is                                    *11.  An   ppropri  te   escription o  re r  ctory   ne  i   with

                             A.   ne  i  , no bl  st                                                                                   excess bl  sts, type 1 RAEB

                             B.   ne  i  , less th n 1% bl  sts                                                                        A.    ne  i  , no bl  sts

                             C.  cytopeni  , less th  n 5% bl  sts, no Auer ro  s                                                      B.   ne  i  , less th n 1% bl  sts

                                                                                                                                       C.  cytopeni  , less th  n 5% bl  sts, no Auer ro  s

                      *10.  An   ppropri  te   escription o  re r  ctory   ne  i   with

                             ring si  erobl  ts (RARS) is                                                                      *12.  In young p  tients, the ther  py o  choice  or MDSs

                             A.    ne  i  , no bl  sts                                                                                 involves

                             B.   ne  i  , less th n 1% bl  sts                                                                        A.  vit    ins

                             C.  cytopeni  , less th  n 5% bl  sts, no Auer ro  s                                                      B.    llogeneic bone     rrow tr  nspl  nt  tion

                                                                                                                                       C.  cytotoxic   rugs

                                                                                                                                       D.  colony-sti  ul  ting growth    ctors











                                                                                                                               Leone G. T er  py-rel  te   leuke  i     n     yelo  yspl  si  : susceptibility
                     COMPANION RES OURCES                                                                                             n   inci  ence, Hemotologica, 92(10):1389–1398, 2007.


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                                                                                                                                     pl  stic syn  ro  es, N Eng J Med, 352(6):549–557, 2005.

                     E  ch stu  ent is encour  ge   to   ccess   n   use the Web-                                              M  lcov  tti L, Dell   Port   MG, P  scutto C, et   l. Prognostic    ctors   n

                     b  se   co  p  nion resources   evelope    or this ch  pter.                                                    li e expect  ncy in   yelo  yspl  stic syn  ro  es cl  ssif e     ccor  ing

                     Here you will f n         ition  l le  rning tools to incre  se                                                 to WHO criteri  :    b  sis  or clinic  l   ecision     king, J Clin Oncol,

                     your un  erst  n  ing o  the concepts   n   clinic  l   pplic  -                                                23(30):7594–7603, 2005.

                     tions o  the ch  pter.                                                                                    Mu  i GJ, Bennett JM, Go  sguen J, et   l. Di  gnosis   n   cl  ssif c  tion
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                                                                                                                                     sus propos  ls  or the   ef nition   n   enu  er  tion o    yelobl  sts   n
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