Page 204 - Clinical Hematology Atlas

188 SECTION FOUR LEUKOCYTES

ature lymphoproliferative disorders frequently are derived from a single clone of cells.
MAlthough this group of diseases involves lymphocytes, the morphological presentation
is variable. The integration of clinical and morphological disease features with immunophe-
notyping is necessary for appropriate recognition and classification. Only representative
samples are included in this atlas.
NOTE: Sustained absolute lymphocytosis in an adult should be investigated to differen-
tiate reactive from malignant processes. Characteristics of reactive lymphocytes are listed in
Table 14-1.

CHRONIC LYMPHOCYTIC LEUKEMIA

A B
FIGURE 19–1A Small lymphocytes with smudge FIGURE 19–1B Albumin smear-same patient as
cells at arrows (PB 3500). presented in figure 19-1A (PB 3500).